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DLL3

Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene. Two transcript variants encoding distinct isoforms have been identified for this gene.

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Aliases
DLL3, SCDO1, pu, pudgy, delta like canonical Notch ligand 3
Band
19q13.2 · 7 A3|7 16.67 cM
Bgee
ganglionic eminence · gonad · testicle · ventricular zone · nucleus accumbens
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 7 (mouse)
Databases
NCBI: entry; OMA: entry

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Function

Clinical significance

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Map overview Semantic statistics

DLL3

Nodes14
Edges13
Triples84
Avg. degree1.86
Density0.142857
Components1

How this topic connects Entity context

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DLL3

Top relations

Bgee · 19
DLL3 → amygdala, anterior cingulate cortex, embryo, epiblast, ganglionic eminence, gonad, hypothalamus, medial ganglionic eminence, morula, nucleus accumbens, pars intermedia, prefrontal cortex, primitive streak, putamen, seminiferous tubule, spermatid, tail of embryo, testicle, ventricular zone
RNA expression pattern · 19
DLL3 → amygdala, anterior cingulate cortex, embryo, epiblast, ganglionic eminence, gonad, hypothalamus, medial ganglionic eminence, morula, nucleus accumbens, pars intermedia, prefrontal cortex, primitive streak, putamen, seminiferous tubule, spermatid, tail of embryo, testicle, ventricular zone
Gene ontology · 14
DLL3 → calcium ion binding, cell differentiation, compartment pattern specification, integral component of membrane, membrane, multicellular organism development, negative regulation of neurogenesis, Notch binding, Notch signaling pathway, paraxial mesoderm development, plasma membrane, skeletal system development, somitogenesis, tissue development
related to Clinical significance · 6
DLL3 → Experimental, Expression, Jarcho-Levin, Mutations, Neuroendocrine, Tarlatamab
related to Function · 6
DLL3 → DSL, EGF, Expression, It, Notch, This
Band · 2
DLL3 → 19q13.2, 7 A3|7 16.67 cM
Chr. · 2
DLL3 → Chromosome 19 (human), Chromosome 7 (mouse)
End · 2
DLL3 → 28,001,663 bp, 39,508,481 bp
Aliases · 1
DLL3 → DLL3, SCDO1, pu, pudgy, delta like canonical Notch ligand 3
BioGPS · 1
DLL3 → More reference expression data

Important terminology Word statistics

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Important terminology

gene bp chr human band chromosome 19 protein location notch mouse expression function external somitogenesis 508 481 end 39 a3

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DLL3AliasesDLL3, SCDO1, pu, pudgy, delta like canonical Notch ligand 31.00infobox
DLL3Band19q13.21.00infobox
DLL3Band7 A3|7 16.67 cM1.00infobox
DLL3Bgeeganglionic eminence1.00infobox
DLL3Bgeegonad1.00infobox
DLL3Bgeetesticle1.00infobox
DLL3Bgeeventricular zone1.00infobox
DLL3Bgeenucleus accumbens1.00infobox
DLL3Bgeeamygdala1.00infobox
DLL3Bgeeanterior cingulate cortex1.00infobox
DLL3Bgeeprefrontal cortex1.00infobox
DLL3Bgeehypothalamus1.00infobox
DLL3Bgeeputamen1.00infobox
DLL3Bgeemedial ganglionic eminence1.00infobox
DLL3Bgeeseminiferous tubule1.00infobox
DLL3Bgeetail of embryo1.00infobox
DLL3Bgeeprimitive streak1.00infobox
DLL3Bgeeembryo1.00infobox
DLL3Bgeeepiblast1.00infobox
DLL3Bgeespermatid1.00infobox
DLL3Bgeemorula1.00infobox
DLL3Bgeepars intermedia1.00infobox
DLL3BioGPSMore reference expression data1.00infobox
DLL3Chr.Chromosome 19 (human)1.00infobox
DLL3Chr.Chromosome 7 (mouse)1.00infobox
DLL3DatabasesNCBI: entry; OMA: entry1.00infobox
DLL3End39,508,481 bp1.00infobox
DLL3End28,001,663 bp1.00infobox
DLL3EnsemblENSG000000909321.00infobox
DLL3Entrez106831.00infobox

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