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DLGAP3: Clinical significance & Overview

Disks large-associated protein 3 (DAP-3) also known as SAP90/PSD-95-associated protein 3 (SAPAP-3) is a protein that in humans is encoded by the DLGAP3 gene.

Language: English [EN]
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DLGAP3 topic overview

The analysis highlights Clinical significance and Overview as prominent areas in the source structure around DLGAP3.

Related topics
4
Source areas
2
Connected nodes
6
Extracted relationships
72
Concept neighborhoods
5
Bridge connections
6

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
DLGAP3, DAP3, SAPAP3, discs large homolog associated protein 3, DLG associated protein 3, SPAPA3
Band
1p34.3 · 4 D2.2|4 61.33 cM
Bgee
right frontal lobe · cingulate gyrus · anterior cingulate cortex · nucleus accumbens · prefrontal cortex
BioGPS
n/a
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How DLGAP3 connects Entity context

The extracted context around DLGAP3 shows recurring relationship patterns in the source. For example, DLGAP3 → amygdala, anterior cingulate cortex, Brodmann area 9, caudate nucleus, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, hippocampus proper, neural layer of retina, nucleus accumbens, nucleus of stria terminalis, prefrontal cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus, temporal lobe Another extracted example is DLGAP3 → amyloid-beta binding, cell junction, cholinergic synapse, glutamatergic synapse, membrane, modification of synaptic structure, neuromuscular junction, plasma membrane, postsynaptic density, postsynaptic membrane, postsynaptic specialization, protein binding, protein domain specific binding, signaling, synapse. Use these groups to spot repeated connection types before inspecting the individual relationships.

DLGAP3

Top relations

Bgee · 18
DLGAP3 → amygdala, anterior cingulate cortex, Brodmann area 9, caudate nucleus, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, hippocampus proper, neural layer of retina, nucleus accumbens, nucleus of stria terminalis, prefrontal cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus, temporal lobe
RNA expression pattern · 18
DLGAP3 → amygdala, anterior cingulate cortex, Brodmann area 9, caudate nucleus, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, hippocampus proper, neural layer of retina, nucleus accumbens, nucleus of stria terminalis, prefrontal cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus, temporal lobe
Gene ontology · 15
DLGAP3 → amyloid-beta binding, cell junction, cholinergic synapse, glutamatergic synapse, membrane, modification of synaptic structure, neuromuscular junction, plasma membrane, postsynaptic density, postsynaptic membrane, postsynaptic specialization, protein binding, protein domain specific binding, signaling, synapse
Band · 2
DLGAP3 → 1p34.3, 4 D2.2|4 61.33 cM
Chr. · 2
DLGAP3 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
DLGAP3 → 127,130,815 bp, 34,929,650 bp
Aliases · 1
DLGAP3 → DLGAP3, DAP3, SAPAP3, discs large homolog associated protein 3, DLG associated protein 3, SPAPA3
BioGPS · 1
DLGAP3 → n/a
Databases · 1
DLGAP3 → NCBI: entry; OMA: entry
Ensembl · 1
DLGAP3 → ENSG00000116544

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp chr human band gene chromosome protein location mouse 929 650 end 34 d2 61 33 130 815 associated disks

DLGAP3 relationships Subject–Predicate–Object triples

TTTA extracted 72 structured relationships around DLGAP3. Examples in this analysis include DLGAP3 → Aliases → DLGAP3, DAP3, SAPAP3, discs large homolog associated protein 3, DLG associated protein 3, SPAPA3 and DLGAP3 → Band → 1p34.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
DLGAP3AliasesDLGAP3, DAP3, SAPAP3, discs large homolog associated protein 3, DLG associated protein 3, SPAPA31.00infobox
DLGAP3Band1p34.31.00infobox
DLGAP3Band4 D2.2|4 61.33 cM1.00infobox
DLGAP3Bgeeright frontal lobe1.00infobox
DLGAP3Bgeecingulate gyrus1.00infobox
DLGAP3Bgeeanterior cingulate cortex1.00infobox
DLGAP3Bgeenucleus accumbens1.00infobox
DLGAP3Bgeeprefrontal cortex1.00infobox
DLGAP3Bgeeputamen1.00infobox
DLGAP3BgeeBrodmann area 91.00infobox
DLGAP3Bgeeamygdala1.00infobox
DLGAP3Bgeecaudate nucleus1.00infobox
DLGAP3Bgeeright hemisphere of cerebellum1.00infobox
DLGAP3Bgeesuperior frontal gyrus1.00infobox
DLGAP3Bgeeprimary visual cortex1.00infobox
DLGAP3Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
DLGAP3Bgeehippocampus proper1.00infobox
DLGAP3Bgeecerebellar cortex1.00infobox
DLGAP3Bgeenucleus of stria terminalis1.00infobox
DLGAP3Bgeetemporal lobe1.00infobox
DLGAP3Bgeeneural layer of retina1.00infobox
DLGAP3BioGPSn/a1.00infobox
DLGAP3Chr.Chromosome 1 (human)1.00infobox
DLGAP3Chr.Chromosome 4 (mouse)1.00infobox
DLGAP3DatabasesNCBI: entry; OMA: entry1.00infobox
DLGAP3End34,929,650 bp1.00infobox
DLGAP3End127,130,815 bp1.00infobox
DLGAP3EnsemblENSG000001165441.00infobox
DLGAP3Entrez585121.00infobox
DLGAP3External IDsOMIM: 611413; MGI: 3039563; GeneCards: DLGAP31.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around DLGAP3 bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Associated. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • DLGAP3
    • Protein
    • Gene
    • Associated
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Clinical
    • Encoded
    • Humans
    • Known
  • dlgap3
    • Protein
    • Gene
    • Associated
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Clinical
    • Encoded
    • Humans
    • Known
  • gene
    • Location
    • Protein
    • Chromosome
    • Human
    • Associated
    • Bp
    • Chr
    • D2
    • End
    • Mouse
    • Band
    • Clinical
  • protein
    • Associated
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Clinical
    • Psd-95-associated
    • References
    • Sap90
    • Sapap-3
    • Significance
  • clinical significance
    • Clinical
    • References
    • Significance
    • Associated
    • Dlgap3
    • Location
    • Protein
    • Chromosome
    • Gene
    • Human
    • Bp
    • Chr

Connections between topic areas Semantic bridges

For DLGAP3, one of the stronger structural bridges in this analysis connects DLGAP3 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
DLGAP3Overview · splits 4 ⟂ 3
DLGAP3Clinical significance · splits 4 ⟂ 3

Map overview Semantic statistics

DLGAP3

Nodes7
Edges6
Triples72
Avg. degree1.71
Density0.285714
Components1

Source & methodology

TTTA analyzes the structure around DLGAP3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — DLGAP3 · EN edition · Analysis: TopicsToTalkAbout

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