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Dexrazoxane: Applications, Medical uses & Mechanism

Dexrazoxane hydrochloride, sold under the brand name Zinecard among others, is a cardioprotective agent. It was discovered in 1972. The IV administration of dexrazoxane is in acidic condition with HCl adjusting the pH.

Language: English [EN]
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Dexrazoxane topic overview

The analysis highlights Applications, Medical uses and Mechanism as prominent areas in the source structure around Dexrazoxane.

Related topics
14
Source areas
2
Connected nodes
16
Extracted relationships
47
Concept neighborhoods
7
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Medical uses · 11 topics
Mechanism · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
V03AF02 (WHO)
CAS Number
24584-09-6 Y
ChEBI
CHEBI:50223 Y
ChEMBL
ChEMBL1738 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Medical uses

Mechanism

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Dexrazoxane connects Entity context

The extracted context around Dexrazoxane shows recurring relationship patterns in the source. For example, Dexrazoxane → CHMP, Committee, Currently, EMA, EU-wide, European Commission, European Medicines Agency, FDA, However, Human Use, July, Medicinal Products, On, That, The, This, US FDA Another extracted example is Dexrazoxane → As, EDTA, It, The. Use these groups to spot repeated connection types before inspecting the individual relationships.

Dexrazoxane

Top relations

related to Medical uses · 17
Dexrazoxane → CHMP, Committee, Currently, EMA, EU-wide, European Commission, European Medicines Agency, FDA, However, Human Use, July, Medicinal Products, On, That, The, This, US FDA
related to Mechanism · 4
Dexrazoxane → As, EDTA, It, The
Legal status · 3
Dexrazoxane → AU: S4 (Prescription only), EU: Rx-only, US: ℞-only
KEGG · 2
Dexrazoxane → as HCl: D07807 Y, D03730 Y
3D model (JSmol) · 1
Dexrazoxane → Interactive image
AHFS/Drugs.com · 1
Dexrazoxane → Monograph
ATC code · 1
Dexrazoxane → V03AF02 (WHO)
CAS Number · 1
Dexrazoxane → 24584-09-6 Y
ChEBI · 1
Dexrazoxane → CHEBI:50223 Y
ChEMBL · 1
Dexrazoxane → ChEMBL1738 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

anthracycline administration anthracyclines drugs name zinecard others hcl use children approved cardioprotective iv mechanism doxorubicin extravasation data us number 19

Dexrazoxane relationships Subject–Predicate–Object triples

TTTA extracted 47 structured relationships around Dexrazoxane. Examples in this analysis include Dexrazoxane → 3D model (JSmol) → Interactive image and Dexrazoxane → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Dexrazoxane3D model (JSmol)Interactive image1.00infobox
DexrazoxaneAHFS/Drugs.comMonograph1.00infobox
DexrazoxaneATC codeV03AF02 (WHO)1.00infobox
DexrazoxaneCAS Number24584-09-6 Y1.00infobox
DexrazoxaneChEBICHEBI:50223 Y1.00infobox
DexrazoxaneChEMBLChEMBL1738 Y1.00infobox
DexrazoxaneChemSpider64479 Y1.00infobox
DexrazoxaneCompTox Dashboard (EPA)DTXSID30406471.00infobox
DexrazoxaneDrugBankDB00380 Y1.00infobox
DexrazoxaneECHA InfoCard100.163.4591.00infobox
DexrazoxaneFormulaC11H16N4O41.00infobox
DexrazoxaneIUPHAR/BPS73301.00infobox
DexrazoxaneKEGGD03730 Y1.00infobox
DexrazoxaneKEGGas HCl: D07807 Y1.00infobox
DexrazoxaneLegal statusAU: S4 (Prescription only)1.00infobox
DexrazoxaneLegal statusUS: ℞-only1.00infobox
DexrazoxaneLegal statusEU: Rx-only1.00infobox
DexrazoxaneLicense dataUS DailyMed: Dexrazoxane1.00infobox
DexrazoxaneMedlinePlusa6090101.00infobox
DexrazoxaneMolar mass268.273 g·mol−11.00infobox
DexrazoxanePubChem CID713841.00infobox
DexrazoxaneRoutes of administrationIntravenous1.00infobox
DexrazoxaneTrade namesZinecard, others1.00infobox
DexrazoxaneUNII048L81261F1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Dexrazoxane bring nearby vocabulary together. In this analysis, examples include Anthracycline, Administration and Anthracyclines. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Dexrazoxane
    • Anthracycline
    • Administration
    • Anthracyclines
    • Approved
    • Children
    • Agents
    • Cardioprotective
    • Chemotherapeutic
    • Data
    • Drugs
    • Hcl
    • Iv
  • dexrazoxane
    • Anthracycline
    • Administration
    • Anthracyclines
    • Approved
    • Children
    • Agents
    • Cardioprotective
    • Chemotherapeutic
    • Data
    • Drugs
    • Hcl
    • Iv
  • food and drug administration
    • Hcl
    • Iv
    • Agents
    • Chemotherapeutic
    • Data
    • Doxorubicin
    • Drugs
    • Extravasation
    • Mechanism
    • Name
    • Number
    • Others
  • doxorubicin
    • Agency
    • Agents
    • Cardioprotection
    • Drugs
    • Ema
    • European
    • Hcl
    • July
    • Mechanism
    • Mg
    • Name
    • Number
  • anthracycline
    • Dexrazoxane
    • Approved
    • Cardioprotection
    • Cardioprotective
    • Currently
    • Decision
    • Ema
    • Extravasation
    • Iv
    • Malignancies
    • Mechanism
    • Number
  • mechanism
    • Agents
    • Chemotherapeutic
    • Data
    • Doxorubicin
    • Drugs
    • Name
    • Number
    • Others
    • Us
    • Used
    • Zinecard
    • Anthracyclines
  • extravasation
    • Iv
    • Use

Connections between topic areas Semantic bridges

For Dexrazoxane, one of the stronger structural bridges in this analysis connects Dexrazoxane with Medical uses. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
DexrazoxaneMedical uses · splits 5 ⟂ 12
DexrazoxaneMechanism · splits 13 ⟂ 4

Map overview Semantic statistics

Dexrazoxane

Nodes17
Edges16
Triples47
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around Dexrazoxane to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Medical uses & Mechanism, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Dexrazoxane · EN edition · Analysis: TopicsToTalkAbout

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