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DCLK1: Overview, Related Topics & Entities

Doublecortin-like kinase protein 1 (DCLK1) is an enzyme that in humans is encoded by the DCLK1 gene. Its C-terminal domain in rats is expressed independently from an alternative transcript, cpg16, and can function alone as a serine/threonine protein kinase that is cyclic AMP dependent.

Language: English [EN]
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DCLK1 topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around DCLK1.

Related topics
5
Source areas
1
Connected nodes
6
Extracted relationships
98
Concept neighborhoods
5
Bridge connections
6

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.1
Aliases
DCLK1, CL1, CLICK1, DCAMKL1, DCDC3A, DCLK, doublecortin like kinase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MFW, 1MG4, 1UF0
Band
13q13.3 · 3|3 C
Bgee
endothelial cell · frontal pole · Brodmann area 10 · Brodmann area 23 · pars reticulata
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How DCLK1 connects Entity context

The extracted context around DCLK1 shows recurring relationship patterns in the source. For example, DCLK1 → ATP binding, axon extension, axonogenesis, brain development, cell differentiation, central nervous system development, central nervous system projection neuron axonogenesis, dendrite morphogenesis, endosomal transport, forebrain development, integral component of plasma membrane, intracellular anatomical structure, intracellular signal transduction, kinase activity, multicellular organism development, negative regulation of protein localization to nucleus, nervous system development, neuron migration, neuron projection morphogenesis, nucleotide binding Another extracted example is DCLK1 → Brodmann area 10, Brodmann area 23, endothelial cell, frontal pole, habenula, middle temporal gyrus, occipital lobe, pars compacta, pars reticulata, piriform cortex, prefrontal cortex, primary motor cortex, primary visual cortex, Rostral migratory stream, stria vascularis, superior frontal gyrus, superior vestibular nucleus, vestibular sensory epithelium, visual cortex. Use these groups to spot repeated connection types before inspecting the individual relationships.

DCLK1

Top relations

Gene ontology · 29
DCLK1 → ATP binding, axon extension, axonogenesis, brain development, cell differentiation, central nervous system development, central nervous system projection neuron axonogenesis, dendrite morphogenesis, endosomal transport, forebrain development, integral component of plasma membrane, intracellular anatomical structure, intracellular signal transduction, kinase activity, multicellular organism development, negative regulation of protein localization to nucleus, nervous system development, neuron migration, neuron projection morphogenesis, nucleotide binding
Bgee · 19
DCLK1 → Brodmann area 10, Brodmann area 23, endothelial cell, frontal pole, habenula, middle temporal gyrus, occipital lobe, pars compacta, pars reticulata, piriform cortex, prefrontal cortex, primary motor cortex, primary visual cortex, Rostral migratory stream, stria vascularis, superior frontal gyrus, superior vestibular nucleus, vestibular sensory epithelium, visual cortex
RNA expression pattern · 19
DCLK1 → Brodmann area 10, Brodmann area 23, endothelial cell, frontal pole, habenula, middle temporal gyrus, occipital lobe, pars compacta, pars reticulata, piriform cortex, prefrontal cortex, primary motor cortex, primary visual cortex, Rostral migratory stream, stria vascularis, superior frontal gyrus, superior vestibular nucleus, vestibular sensory epithelium, visual cortex
related to External links · 6
DCLK1 → O15075, Overview, PDB, PDBe-KB, Serine/threonine-protein, UniProt
Band · 2
DCLK1 → 13q13.3, 3|3 C
Chr. · 2
DCLK1 → Chromosome 13 (human), Chromosome 3 (mouse)
End · 2
DCLK1 → 36,131,382 bp, 55,446,489 bp
2.7.11.1 · 1
DCLK1 → ↗
Aliases · 1
DCLK1 → DCLK1, CL1, CLICK1, DCAMKL1, DCDC3A, DCLK, doublecortin like kinase 1
Available structures · 1
DCLK1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MFW, 1MG4, 1UF0

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp kinase chr human band gene chromosome 13 protein serine location enzyme mouse expressed function threonine expression cell epithelium external

DCLK1 relationships Subject–Predicate–Object triples

TTTA extracted 98 structured relationships around DCLK1. Examples in this analysis include DCLK1 → 2.7.11.1 → ↗ and DCLK1 → Aliases → DCLK1, CL1, CLICK1, DCAMKL1, DCDC3A, DCLK, doublecortin like kinase 1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
DCLK12.7.11.11.00infobox
DCLK1AliasesDCLK1, CL1, CLICK1, DCAMKL1, DCDC3A, DCLK, doublecortin like kinase 11.00infobox
DCLK1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MFW, 1MG4, 1UF01.00infobox
DCLK1Band13q13.31.00infobox
DCLK1Band3|3 C1.00infobox
DCLK1Bgeeendothelial cell1.00infobox
DCLK1Bgeefrontal pole1.00infobox
DCLK1BgeeBrodmann area 101.00infobox
DCLK1BgeeBrodmann area 231.00infobox
DCLK1Bgeepars reticulata1.00infobox
DCLK1Bgeepars compacta1.00infobox
DCLK1Bgeeoccipital lobe1.00infobox
DCLK1Bgeemiddle temporal gyrus1.00infobox
DCLK1Bgeesuperior vestibular nucleus1.00infobox
DCLK1Bgeeprimary visual cortex1.00infobox
DCLK1Bgeestria vascularis1.00infobox
DCLK1BgeeRostral migratory stream1.00infobox
DCLK1Bgeepiriform cortex1.00infobox
DCLK1Bgeevestibular sensory epithelium1.00infobox
DCLK1Bgeehabenula1.00infobox
DCLK1Bgeevisual cortex1.00infobox
DCLK1Bgeesuperior frontal gyrus1.00infobox
DCLK1Bgeeprimary motor cortex1.00infobox
DCLK1Bgeeprefrontal cortex1.00infobox
DCLK1BioGPSMore reference expression data1.00infobox
DCLK1Chr.Chromosome 13 (human)1.00infobox
DCLK1Chr.Chromosome 3 (mouse)1.00infobox
DCLK1DatabasesNCBI: entry; OMA: entry1.00infobox
DCLK1End36,131,382 bp1.00infobox
DCLK1End55,446,489 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around DCLK1 bring nearby vocabulary together. In this analysis, examples include Gene, Kinase and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • DCLK1
    • Gene
    • Kinase
    • Activity
    • Available
    • Cell
    • Enzyme
    • Epithelium
    • Expression
    • Pdb
    • Search
    • Location
    • Protein
  • dclk1
    • Gene
    • Kinase
    • Activity
    • Available
    • Cell
    • Enzyme
    • Epithelium
    • Expression
    • Pdb
    • Search
    • Location
    • Protein
  • gene
    • Location
    • Chromosome
    • Human
    • Kinase
    • Activity
    • Available
    • Bp
    • Chr
    • End
    • Mouse
    • Pdb
    • Search
  • serine/threonine protein kinase
    • Threonine
    • Protein
    • Serine
    • Gene
    • Activity
    • Available
    • Enzyme
    • Expressed
    • Function
    • O15075
    • Pdb
    • Search
  • enzyme
    • Encoded
    • External
    • Gene
    • Humans
    • Kinase
    • Activity
    • Available
    • Pdb
    • Search
    • Location
    • Protein
    • Chromosome

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the DCLK1 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

DCLK1

Nodes7
Edges6
Triples98
Avg. degree1.71
Density0.285714
Components1

Source & methodology

TTTA analyzes the structure around DCLK1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — DCLK1 · EN edition · Analysis: TopicsToTalkAbout

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