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DCLK1

Doublecortin-like kinase protein 1 (DCLK1) is an enzyme that in humans is encoded by the DCLK1 gene. Its C-terminal domain in rats is expressed independently from an alternative transcript, cpg16, and can function alone as a serine/threonine protein kinase that is cyclic AMP dependent.

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2.7.11.1
Aliases
DCLK1, CL1, CLICK1, DCAMKL1, DCDC3A, DCLK, doublecortin like kinase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MFW, 1MG4, 1UF0
Band
13q13.3 · 3|3 C
Bgee
endothelial cell · frontal pole · Brodmann area 10 · Brodmann area 23 · pars reticulata
BioGPS
More reference expression data

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DCLK1

Nodes7
Edges6
Triples98
Avg. degree1.71
Density0.285714
Components1

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DCLK1

Top relations

Gene ontology · 29
DCLK1 → ATP binding, axon extension, axonogenesis, brain development, cell differentiation, central nervous system development, central nervous system projection neuron axonogenesis, dendrite morphogenesis, endosomal transport, forebrain development, integral component of plasma membrane, intracellular anatomical structure, intracellular signal transduction, kinase activity, multicellular organism development, negative regulation of protein localization to nucleus, nervous system development, neuron migration, neuron projection morphogenesis, nucleotide binding
Bgee · 19
DCLK1 → Brodmann area 10, Brodmann area 23, endothelial cell, frontal pole, habenula, middle temporal gyrus, occipital lobe, pars compacta, pars reticulata, piriform cortex, prefrontal cortex, primary motor cortex, primary visual cortex, Rostral migratory stream, stria vascularis, superior frontal gyrus, superior vestibular nucleus, vestibular sensory epithelium, visual cortex
RNA expression pattern · 19
DCLK1 → Brodmann area 10, Brodmann area 23, endothelial cell, frontal pole, habenula, middle temporal gyrus, occipital lobe, pars compacta, pars reticulata, piriform cortex, prefrontal cortex, primary motor cortex, primary visual cortex, Rostral migratory stream, stria vascularis, superior frontal gyrus, superior vestibular nucleus, vestibular sensory epithelium, visual cortex
related to External links · 6
DCLK1 → O15075, Overview, PDB, PDBe-KB, Serine/threonine-protein, UniProt
Band · 2
DCLK1 → 13q13.3, 3|3 C
Chr. · 2
DCLK1 → Chromosome 13 (human), Chromosome 3 (mouse)
End · 2
DCLK1 → 36,131,382 bp, 55,446,489 bp
2.7.11.1 · 1
DCLK1 → ↗
Aliases · 1
DCLK1 → DCLK1, CL1, CLICK1, DCAMKL1, DCDC3A, DCLK, doublecortin like kinase 1
Available structures · 1
DCLK1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MFW, 1MG4, 1UF0

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Important terminology

bp kinase chr human band gene chromosome 13 protein serine location enzyme mouse expressed function threonine expression cell epithelium external

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DCLK12.7.11.11.00infobox
DCLK1AliasesDCLK1, CL1, CLICK1, DCAMKL1, DCDC3A, DCLK, doublecortin like kinase 11.00infobox
DCLK1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MFW, 1MG4, 1UF01.00infobox
DCLK1Band13q13.31.00infobox
DCLK1Band3|3 C1.00infobox
DCLK1Bgeeendothelial cell1.00infobox
DCLK1Bgeefrontal pole1.00infobox
DCLK1BgeeBrodmann area 101.00infobox
DCLK1BgeeBrodmann area 231.00infobox
DCLK1Bgeepars reticulata1.00infobox
DCLK1Bgeepars compacta1.00infobox
DCLK1Bgeeoccipital lobe1.00infobox
DCLK1Bgeemiddle temporal gyrus1.00infobox
DCLK1Bgeesuperior vestibular nucleus1.00infobox
DCLK1Bgeeprimary visual cortex1.00infobox
DCLK1Bgeestria vascularis1.00infobox
DCLK1BgeeRostral migratory stream1.00infobox
DCLK1Bgeepiriform cortex1.00infobox
DCLK1Bgeevestibular sensory epithelium1.00infobox
DCLK1Bgeehabenula1.00infobox
DCLK1Bgeevisual cortex1.00infobox
DCLK1Bgeesuperior frontal gyrus1.00infobox
DCLK1Bgeeprimary motor cortex1.00infobox
DCLK1Bgeeprefrontal cortex1.00infobox
DCLK1BioGPSMore reference expression data1.00infobox
DCLK1Chr.Chromosome 13 (human)1.00infobox
DCLK1Chr.Chromosome 3 (mouse)1.00infobox
DCLK1DatabasesNCBI: entry; OMA: entry1.00infobox
DCLK1End36,131,382 bp1.00infobox
DCLK1End55,446,489 bp1.00infobox

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