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Darbepoetin alfa

Darbepoetin alfa (INN) /dɑːrbəˈpoʊɪtɪn/ is a re-engineered form of erythropoietin containing 5 amino acid changes (N30, T32, V87, N88, T90) resulting in the creation of 2 new sites for N-linked carbohydrate addition. It has a 3-fold longer serum half-life compared to epoetin alpha and epoetin beta. It stimulates erythropoiesis (increases red blood cell…

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Key facts & relationships

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AHFS/Drugs.com
Monograph
ATC code
B03XA02 (WHO)
CAS Number
209810-58-2 N
ChemSpider
none
CompTox Dashboard (EPA)
DTXSID7039678
DrugBank
DB00012 Y

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Overview

Adverse effects

Mechanism of action

Safety advisories in anemic cancer patients

Society and culture

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Map overview Semantic statistics

Darbepoetin alfa

Nodes49
Edges48
Triples39
Avg. degree1.96
Density0.040816
Components1

How this topic connects Entity context

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Darbepoetin alfa

Top relations

related to Society and culture · 8
Darbepoetin alfa → Its, Johann Mühlegg, Larisa Lazutina, Like EPO, Olga Danilova, Russia, Spain, Winter Olympic Games
has effect · 6
Darbepoetin alfa → Darbepoetin, In, Other, RBC, To, United States
Legal status · 4
Darbepoetin alfa → AU: S4 (Prescription only), EU: Rx-only, In general: ℞ (Prescription only), US: ℞-only
related to Pregnancy and lactation · 3
Darbepoetin alfa → Darbepoetin, It, United States
related to Mechanism of action · 2
Darbepoetin alfa → Darbepoetin, RBC
AHFS/Drugs.com · 1
Darbepoetin alfa → Monograph
ATC code · 1
Darbepoetin alfa → B03XA02 (WHO)
CAS Number · 1
Darbepoetin alfa → 209810-58-2 N
ChemSpider · 1
Darbepoetin alfa → none
CompTox Dashboard (EPA) · 1
Darbepoetin alfa → DTXSID7039678

Important terminology Word statistics

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Important terminology

darbepoetin alfa patients cancer anemia use chemotherapy failure aranesp erythropoietin epo chronic kidney treatment administration amgen pregnancy clinical red cell

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Darbepoetin alfaAHFS/Drugs.comMonograph1.00infobox
Darbepoetin alfaATC codeB03XA02 (WHO)1.00infobox
Darbepoetin alfaCAS Number209810-58-2 N1.00infobox
Darbepoetin alfaChemSpidernone1.00infobox
Darbepoetin alfaCompTox Dashboard (EPA)DTXSID70396781.00infobox
Darbepoetin alfaDrugBankDB00012 Y1.00infobox
Darbepoetin alfaFormulaC815H1317N233O241S51.00infobox
Darbepoetin alfaLegal statusAU: S4 (Prescription only)1.00infobox
Darbepoetin alfaLegal statusUS: ℞-only1.00infobox
Darbepoetin alfaLegal statusEU: Rx-only1.00infobox
Darbepoetin alfaLegal statusIn general: ℞ (Prescription only)1.00infobox
Darbepoetin alfaLicense dataUS DailyMed: Darbepoetin alfa1.00infobox
Darbepoetin alfaMedlinePlusa6040221.00infobox
Darbepoetin alfaMolar mass18396.19 g·mol−11.00infobox
Darbepoetin alfaPregnancy categoryAU: B31.00infobox
Darbepoetin alfaRoutes of administrationIntravenous, subcutaneous1.00infobox
Darbepoetin alfaTrade namesAranesp1.00infobox
Darbepoetin alfaUNII15UQ94PT4P1.00infobox

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