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Cyclorphan

Cyclorphan is an opioid analgesic of the morphinan family that was never marketed. It acts as a μ-opioid receptor (MOR) weak partial agonist or antagonist, κ-opioid receptor (KOR) full agonist, and, to a much lesser extent, δ-opioid receptor (DOR) agonist (75-fold lower affinity relative to the KOR). The drug was first synthesized in 1964 by scientists…

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3D model (JSmol)
Interactive image
Boiling point
458.4 °C (857.1 °F)
CAS Number
4163-15-9
ChEMBL
ChEMBL49269
ChemSpider
4514407
CompTox Dashboard (EPA)
DTXSID50878519

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Overview

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Map overview Semantic statistics

Cyclorphan

Nodes15
Edges14
Triples14
Avg. degree1.87
Density0.133333
Components1

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Cyclorphan

Top relations

3D model (JSmol) · 1
Cyclorphan → Interactive image
Boiling point · 1
Cyclorphan → 458.4 °C (857.1 °F)
CAS Number · 1
Cyclorphan → 4163-15-9
ChEMBL · 1
Cyclorphan → ChEMBL49269
ChemSpider · 1
Cyclorphan → 4514407
CompTox Dashboard (EPA) · 1
Cyclorphan → DTXSID50878519
Density · 1
Cyclorphan → 1.19 g/cm3
ECHA InfoCard · 1
Cyclorphan → 100.021.825
Formula · 1
Cyclorphan → C20H27NO
Melting point · 1
Cyclorphan → 188 °C (370 °F)

Important terminology Word statistics

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Important terminology

kor opioid analgesic morphinan antagonist affinity psychotomimetic family never marketed acts μ-opioid receptor mor weak partial agonist κ-opioid full much

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cyclorphan3D model (JSmol)Interactive image1.00infobox
CyclorphanBoiling point458.4 °C (857.1 °F)1.00infobox
CyclorphanCAS Number4163-15-91.00infobox
CyclorphanChEMBLChEMBL492691.00infobox
CyclorphanChemSpider45144071.00infobox
CyclorphanCompTox Dashboard (EPA)DTXSID508785191.00infobox
CyclorphanDensity1.19 g/cm31.00infobox
CyclorphanECHA InfoCard100.021.8251.00infobox
CyclorphanFormulaC20H27NO1.00infobox
CyclorphanMelting point188 °C (370 °F)1.00infobox
CyclorphanMolar mass297.442 g·mol−11.00infobox
CyclorphanPubChem CID53599661.00infobox
CyclorphanUNIIU6Z73N36V01.00infobox
Cyclorphanis aopioid analgesic of the morphinan family that was never marketed0.90text

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