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CX-516: Overview, Related Topics & Entities

CX-516 is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator and had been undergoing development by a collaboration between Cortex, Shire, and Servier. It was studied as a potential treatment for Alzheimer's disease under the brand name Ampalex, and was also being examined as a treatment for ADHD.

Language: English [EN]
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CX-516 topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around CX-516.

Related topics
12
Source areas
1
Connected nodes
13
Extracted relationships
27
Concept neighborhoods
14
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 12 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
CAS Number
154235-83-3 Y
ChEMBL
ChEMBL136800 Y
ChemSpider
130635 Y
CompTox Dashboard (EPA)
DTXSID70165574
ECHA InfoCard
100.237.047

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CX-516 connects Entity context

The extracted context around CX-516 shows recurring relationship patterns in the source. For example, CX-516 → Current Opinion, CX-516 Cortex, Danysz, Investigational Drugs, July, Lock-gray-alt-2, Lock-green, Lock-red-alt-2, PMID, Wikisource-logo Another extracted example is CX-516 → Interactive image. Use these groups to spot repeated connection types before inspecting the individual relationships.

CX-516

Top relations

related to References · 10
CX-516 → Current Opinion, CX-516 Cortex, Danysz, Investigational Drugs, July, Lock-gray-alt-2, Lock-green, Lock-red-alt-2, PMID, Wikisource-logo
3D model (JSmol) · 1
CX-516 → Interactive image
CAS Number · 1
CX-516 → 154235-83-3 Y
ChEMBL · 1
CX-516 → ChEMBL136800 Y
ChemSpider · 1
CX-516 → 130635 Y
CompTox Dashboard (EPA) · 1
CX-516 → DTXSID70165574
ECHA InfoCard · 1
CX-516 → 100.237.047
Elimination half-life · 1
CX-516 → 45 minutes
Formula · 1
CX-516 → C14H15N3O
IUPHAR/BPS · 1
CX-516 → 4165

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

ampakine cortex positive compound animal also name ampalex half-life ampa receptor allosteric modulator drugs mw-parser-output font-weight nootropic development shire servier

CX-516 relationships Subject–Predicate–Object triples

TTTA extracted 27 structured relationships around CX-516. Examples in this analysis include CX-516 → 3D model (JSmol) → Interactive image and CX-516 → CAS Number → 154235-83-3 Y. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CX-5163D model (JSmol)Interactive image1.00infobox
CX-516CAS Number154235-83-3 Y1.00infobox
CX-516ChEMBLChEMBL136800 Y1.00infobox
CX-516ChemSpider130635 Y1.00infobox
CX-516CompTox Dashboard (EPA)DTXSID701655741.00infobox
CX-516ECHA InfoCard100.237.0471.00infobox
CX-516Elimination half-life45 minutes1.00infobox
CX-516FormulaC14H15N3O1.00infobox
CX-516IUPHAR/BPS41651.00infobox
CX-516KEGGC13675 Y1.00infobox
CX-516Molar mass241.294 g·mol−11.00infobox
CX-516PubChem CID1481841.00infobox
CX-516Trade namesAmpalex1.00infobox
CX-516UNIIZ5QU38B4V91.00infobox
CX-516is aampakine and nootropic that acts as an AMPA receptor positive allosteric modulator and had been undergoing development by a collaboration between Cortex0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around CX-516 bring nearby vocabulary together. In this analysis, examples include Cortex, Positive and Allosteric. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CX-516
    • Cortex
    • Positive
    • Allosteric
    • Ampa
    • Animal
    • Compound
    • Half-life
    • Modulator
    • Receptor
    • Acts
    • Cx-717
    • Developed
  • cx-516
    • Cortex
    • Positive
    • Allosteric
    • Ampa
    • Animal
    • Compound
    • Half-life
    • Modulator
    • Receptor
    • Acts
    • Cx-717
    • Developed
  • ampakine
    • Cx-516
    • Animal
    • Compound
    • Cortex
    • Positive
    • Activity
    • Acts
    • Collaboration
    • Cx-717
    • Developed
    • Development
    • Farampator
  • positive allosteric modulator
    • Ampa
    • Modulator
    • Receptor
    • Cortex
    • Half-life
    • Positive
    • Collaboration
    • Cx-516
    • Development
    • Font-weight
    • Mw-parser-output
    • Nootropic
  • cortex
    • Positive
    • Cx-516
    • Half-life
    • Modulator
    • Receptor
    • Activity
    • Developed
    • Development
    • First
    • Font-weight
    • Good
    • Mw-parser-output
  • ampa receptor
    • Allosteric
    • Modulator
    • Receptor
    • Cortex
    • Positive
    • Collaboration
    • Cx-516
    • Development
    • Font-weight
    • Mw-parser-output
    • Nootropic
    • Servier
  • alzheimer's disease
    • Adhd
    • Brand
    • Disease
    • Examined
    • Potential
    • Studied
    • Treatment
    • Also
    • Ampalex
    • Name
  • adhd
    • Alzheimer's
    • Brand
    • Disease
    • Examined
    • Potential
    • Studied
    • Treatment
    • Also
    • Ampalex
    • Name

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the CX-516 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

CX-516

Nodes14
Edges13
Triples27
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around CX-516 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CX-516 · EN edition · Analysis: TopicsToTalkAbout

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