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Click chemistry

Click chemistry is an approach to chemical synthesis that is used to join two molecules. The application of the term, click, as a qualifier to the type of chemistry refers to an emphasis on efficiency and simplicity. To link two molecular components, each is first fitted with appropriate functional groups, such as azide and alkyne groups. These…

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History, Technology & Applications

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Explore the main themes, entities and connections around Click chemistry. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.

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Overview

History

Click reactions

Potential applications

Technology license

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

Click chemistry

Nodes62
Edges61
Triples54
Avg. degree1.97
Density0.032258
Components1

How this topic connects Entity context

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Click chemistry

Top relations

related to External links · 15
Click chemistry → Chem Soc Rev, Chemical, Chemistry, Copper-free Click Chemistry, Engineering News, Feature, Finn, Going Live, In-Situ Click Chemistry, Metal-free, Published, Recent LiteratureNational Science Foundation, Royal Society, Short Review, Valery Fokin
related to Technology license · 10
Click chemistry → Aileron, Allozyne, BASF, Cyandye, Fluorescent, Integrated Diagnostics, Invitrogen, Licensees, Moreover, The Scripps Research Institute
related to history · 8
Click chemistry → Barry Sharpless, Finn, Hartmuth, Kolb, Many, Some, The, The Scripps Research Institute
related to Selective labeling and tracking of biomolecules · 7
Click chemistry → Click, Examples, GFP, In, One, SPAAC, The
related to Drug discovery and bio-conjugation · 6
Click chemistry → Click, Discoveries, II, Its, Recent, The
is a · 1
Click chemistry → approach to chemical synthesis that is used to join two molecules

Important terminology Word statistics

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Important terminology

reaction click chemistry reactions groups azide cycloaddition include used strained alkenes applications labeling bioconjugation alkyne react may synthesis first many

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
Click chemistryis aapproach to chemical synthesis that is used to join two molecules0.90text
oxanorbornadiene react in click reactions with a number of partners including azidesinstance ofand other strained alkenes0.80text
tetrazinesinstance ofand other strained alkenes0.80text
and tetrazolesinstance ofand other strained alkenes0.80text
the 1instance ofnatural groups0.80text
2-aminothiolinstance ofnatural groups0.80text
which appears only when a cysteine is the final N' amino acid in a proteininstance ofnatural groups0.80text
Cyandyeinstance ofFluorescent azides and alkynes are also produced by companies0.80text
Click chemistryrelated to Drug discovery and bio-conjugationClick0.60section
Click chemistryrelated to Drug discovery and bio-conjugationIts0.60section
Click chemistryrelated to Drug discovery and bio-conjugationRecent0.60section
Click chemistryrelated to Drug discovery and bio-conjugationThe0.60section

Related concept clusters Concept neighborhoods

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