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CU-CPT9a

CU-CPT9a is a drug which acts as a potent and selective antagonist of Toll-like receptor 8 (TLR8), with an IC50 of 0.5nM. Activation of toll-like receptors triggers release of cytokines and other signalling factors, leading to inflammation. This is an essential part of the immune system's response to infection, but chronic activation of TLR signalling is…

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3D model (JSmol)
Interactive image
CAS Number
2165340-32-7
ChemSpider
65323639
Formula
C17H15NO2
Molar mass
265.312 g·mol−1
PubChem CID
135567383

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Overview

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Map overview Semantic statistics

CU-CPT9a

Nodes7
Edges6
Triples8
Avg. degree1.71
Density0.285714
Components1

How this topic connects Entity context

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CU-CPT9a

Top relations

3D model (JSmol) · 1
CU-CPT9a → Interactive image
CAS Number · 1
CU-CPT9a → 2165340-32-7
ChemSpider · 1
CU-CPT9a → 65323639
Formula · 1
CU-CPT9a → C17H15NO2
Molar mass · 1
CU-CPT9a → 265.312 g·mol−1
PubChem CID · 1
CU-CPT9a → 135567383
UNII · 1
CU-CPT9a → 6BNV86VAQ8
is a · 1
CU-CPT9a → drug which acts as a potent and selective antagonist of Toll-like receptor 8

Important terminology Word statistics

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Important terminology

toll-like tlr8 activation signalling autoimmune disorders cytokines inflammation immunosuppressant drug acts potent selective antagonist receptor ic50 5nm receptors triggers release

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CU-CPT9a3D model (JSmol)Interactive image1.00infobox
CU-CPT9aCAS Number2165340-32-71.00infobox
CU-CPT9aChemSpider653236391.00infobox
CU-CPT9aFormulaC17H15NO21.00infobox
CU-CPT9aMolar mass265.312 g·mol−11.00infobox
CU-CPT9aPubChem CID1355673831.00infobox
CU-CPT9aUNII6BNV86VAQ81.00infobox
CU-CPT9ais adrug which acts as a potent and selective antagonist of Toll-like receptor 80.90text

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