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Colipase: Protein domain & Overview

Colipase, abbreviated CLPS, is a protein co-enzyme that counteracts the inhibitory effect of intestinal bile acid on the enzymatic activity of pancreatic lipase. It is secreted by the pancreas in an inactive form, procolipase, which is activated by trypsin in the intestinal lumen.

Language: English [EN]
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Colipase topic overview

The analysis highlights Protein domain and Overview as prominent areas in the source structure around Colipase.

Related topics
12
Source areas
2
Connected nodes
14
Extracted relationships
73
Related term clusters
10
Bridge connections
14

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 10 topics
Protein domain · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CLPS, entrez:1208, colipase
Band
6p21.31 · 17|17 A3.3
Bgee
body of pancreas · islet of Langerhans · testicle · pancreatic epithelial cell · beta cell
BioGPS
More reference expression data
Chr.
Chromosome 6 (human) · Chromosome 17 (mouse)
Databases
NCBI: entry; OMA: entry

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Colipase

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Protein domain

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Colipase connects Entity context

The extracted context around Colipase shows recurring relationship patterns in the source. For example, Colipase → beta cell, body of pancreas, colon, Descending thoracic aorta, duodenum, ectocervix, esophagus, ileum, islet of Langerhans, jejunum, morula, pancreatic epithelial cell, quadriceps femoris muscle, right coronary artery, right lobe of liver, right uterine tube, stomach, testicle, yolk sac Another extracted example is Colipase → digestion, enzyme activator activity, extracellular region, lipid catabolic process, lipid digestion, lipid metabolism, positive regulation of catalytic activity, response to bacterium, response to food, retinoid metabolic process. Use these groups to spot repeated connection types before inspecting the individual relationships.

Colipase

Top relations

Bgee · 19
Colipase → beta cell, body of pancreas, colon, Descending thoracic aorta, duodenum, ectocervix, esophagus, ileum, islet of Langerhans, jejunum, morula, pancreatic epithelial cell, quadriceps femoris muscle, right coronary artery, right lobe of liver, right uterine tube, stomach, testicle, yolk sac
RNA expression pattern · 19
Colipase → beta cell, body of pancreas, colon, Descending thoracic aorta, duodenum, ectocervix, esophagus, ileum, islet of Langerhans, jejunum, morula, pancreatic epithelial cell, quadriceps femoris muscle, right coronary artery, right lobe of liver, right uterine tube, stomach, testicle, yolk sac
Gene ontology · 10
Colipase → digestion, enzyme activator activity, extracellular region, lipid catabolic process, lipid digestion, lipid metabolism, positive regulation of catalytic activity, response to bacterium, response to food, retinoid metabolic process
related to Protein domain · 3
Colipase → C-terminal, Efficient, Structural
Band · 2
Colipase → 17|17 A3.3, 6p21.31
Chr. · 2
Colipase → Chromosome 17 (mouse), Chromosome 6 (human)
End · 2
Colipase → 28,779,740 bp, 35,797,344 bp
is a · 2
Colipase → small protein, small protein cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis
Aliases · 1
Colipase → CLPS, entrez:1208, colipase
BioGPS · 1
Colipase → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein lipase bp clps pancreatic chr human band gene chromosome intestinal bile also lipid location binding acids surface droplet precursor

Colipase relationships Subject–Predicate–Object triples

TTTA extracted 73 structured relationships around Colipase. Examples in this analysis include Colipase → Aliases → CLPS, entrez:1208, colipase and Colipase → Band → 6p21.31. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ColipaseAliasesCLPS, entrez:1208, colipase1.00infobox
ColipaseBand6p21.311.00infobox
ColipaseBand17|17 A3.31.00infobox
ColipaseBgeebody of pancreas1.00infobox
ColipaseBgeeislet of Langerhans1.00infobox
ColipaseBgeetesticle1.00infobox
ColipaseBgeepancreatic epithelial cell1.00infobox
ColipaseBgeebeta cell1.00infobox
ColipaseBgeeright coronary artery1.00infobox
ColipaseBgeeectocervix1.00infobox
ColipaseBgeeright uterine tube1.00infobox
ColipaseBgeeDescending thoracic aorta1.00infobox
ColipaseBgeeright lobe of liver1.00infobox
ColipaseBgeestomach1.00infobox
ColipaseBgeejejunum1.00infobox
ColipaseBgeeduodenum1.00infobox
ColipaseBgeecolon1.00infobox
ColipaseBgeeileum1.00infobox
ColipaseBgeeesophagus1.00infobox
ColipaseBgeemorula1.00infobox
ColipaseBgeequadriceps femoris muscle1.00infobox
ColipaseBgeeyolk sac1.00infobox
ColipaseBioGPSMore reference expression data1.00infobox
ColipaseChr.Chromosome 6 (human)1.00infobox
ColipaseChr.Chromosome 17 (mouse)1.00infobox
ColipaseDatabasesNCBI: entry; OMA: entry1.00infobox
ColipaseEnd35,797,344 bp1.00infobox
ColipaseEnd28,779,740 bp1.00infobox
ColipaseEnsemblENSG000001373921.00infobox
ColipaseEntrez12081.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Colipase bring nearby vocabulary together. In this analysis, examples include Protein, Lipase and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Colipase
    • Protein
    • Lipase
    • Gene
    • Pancreatic
    • Activity
    • Entrez
    • Bile
    • Binding
    • Domain
    • Lipid
    • Location
    • Also
  • colipase
    • Protein
    • Lipase
    • Gene
    • Pancreatic
    • Activity
    • Entrez
    • Bile
    • Binding
    • Domain
    • Lipid
    • Location
    • Also
  • protein
    • Pancreatic
    • Colipase
    • Also
    • Clps
    • Lipase
    • Gene
    • Activity
    • Entrez
    • Precursor
    • Domain
    • Domains
    • Lipid
  • pancreatic lipase
    • Lipase
    • Pancreatic
    • Protein
    • Binding
    • Domains
    • Lipid
    • Acids
    • Active
    • Also
    • Droplet
    • Surface
    • Domain
  • protein domain
    • Pancreatic
    • Colipase
    • Also
    • Clps
    • External
    • Lipase
    • Gene
    • Entrez
    • Activity
    • Precursor
    • Domain
    • Domains
  • gene
    • Location
    • Chromosome
    • Human
    • A3
    • Bp
    • Chr
    • End
    • Entrez
    • Mouse
    • Also
    • Band
    • Protein
  • bile acid
    • Acids
    • Droplet
    • Surface
    • Intestinal
    • Lipase
    • Co-enzyme
    • Active
    • Activity
    • Digestion
    • Binding
    • Lipid
    • Colipase
  • co-enzyme
    • Activity
    • Bile
    • Intestinal
    • Pancreatic
    • Lipase
    • Protein
    • Colipase

Connections between topic areas Semantic bridges

For Colipase, one of the stronger structural bridges in this analysis connects Colipase with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Colipase — Overview · splits 4 ⟂ 11
Colipase — Protein domain · splits 12 ⟂ 3

Map overview Semantic statistics

Colipase

Nodes15
Edges14
Triples73
Avg. degree1.87
Density0.133333
Components1

Source & methodology

TTTA analyzes the structure around Colipase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Protein domain & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Colipase · EN edition · Analysis: TopicsToTalkAbout

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