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The process of immunological B-cell maturation involves transformation from an undifferentiated B cell to one that secretes antibodies with particular specificity. This differentiation and activation of the B cell occurs most rapidly after exposure to antigen by antigen-presenting cells in the reticuloendothelial system, and under modulation by T cells…
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Explore the main themes, entities and connections around Clone (B-cell). Start with the topic map, then use the sections below for research and deeper semantic analysis.
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cells cell antibodies expansion clone b-cell malignancy process maturation particular antigen closely illnesses also reticuloendothelial lymphocytic neoplastic lymphoma amyloidosis lupus
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| multiple myeloma | instance of | a process known as clonal selection.In lymphocytic neoplastic diseases | 0.80 | text |
| lymphoma | instance of | a process known as clonal selection.In lymphocytic neoplastic diseases | 0.80 | text |
| but also other illnesses | instance of | a process known as clonal selection.In lymphocytic neoplastic diseases | 0.80 | text |
| there can be a massive expansion of a single B-cell clone | instance of | a process known as clonal selection.In lymphocytic neoplastic diseases | 0.80 | text |
| detectable by measuring the excessively-produced antibodies | instance of | a process known as clonal selection.In lymphocytic neoplastic diseases | 0.80 | text |
| measured in a serum protein electrophoresis test or peripheral blood flow cytometry | instance of | a process known as clonal selection.In lymphocytic neoplastic diseases | 0.80 | text |
| amyloidosis | instance of | and monoclonal antibodies produced by such a group of B cells can cause illnesses | 0.80 | text |
| lupus | instance of | and monoclonal antibodies produced by such a group of B cells can cause illnesses | 0.80 | text |
| or can be indicative of an underlying malignancy | instance of | and monoclonal antibodies produced by such a group of B cells can cause illnesses | 0.80 | text |
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