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CLCNKA: Standards, Function & Pathology

Chloride channel protein ClC-Ka is a protein that in humans is encoded by the CLCNKA gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Language: English [EN]
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CLCNKA topic overview

The analysis highlights Standards, Function and Pathology as prominent areas in the source structure around CLCNKA.

Related topics
10
Source areas
4
Connected nodes
14
Extracted relationships
104
Concept neighborhoods
8
Bridge connections
14

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 3 topics
Pathology · 3 topics
Gene variants · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CLCNKA, CLCK1, ClC-K1, hClC-Ka, chloride voltage-gated channel Ka
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2PFI
Band
1p36.13 · 4|4 D3
Bgee
left lobe of thyroid gland · right lobe of thyroid gland · pituitary gland · anterior pituitary · body of pancreas
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Gene variants

Pathology

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CLCNKA connects Entity context

The extracted context around CLCNKA shows recurring relationship patterns in the source. For example, CLCNKA → anterior pituitary, blastocyst, body of pancreas, body of stomach, connecting tubule, distal tubule, human kidney, inner renal medulla, inner stripe of outer renal medulla, left lobe of thyroid gland, morula, outer renal medulla, pituitary gland, right adrenal cortex, right hemisphere of cerebellum, right kidney, right lobe of thyroid gland, submandibular gland, testicle Another extracted example is CLCNKA → chloride channel activity, chloride channel complex, chloride transmembrane transport, chloride transport, excretion, identical protein binding, integral component of membrane, integral component of plasma membrane, ion transmembrane transport, ion transport, membrane, metal ion binding, plasma membrane, regulation of ion transmembrane transport, transmembrane transport, voltage-gated chloride channel activity, voltage-gated ion channel activity. Use these groups to spot repeated connection types before inspecting the individual relationships.

CLCNKA

Top relations

Bgee · 19
CLCNKA → anterior pituitary, blastocyst, body of pancreas, body of stomach, connecting tubule, distal tubule, human kidney, inner renal medulla, inner stripe of outer renal medulla, left lobe of thyroid gland, morula, outer renal medulla, pituitary gland, right adrenal cortex, right hemisphere of cerebellum, right kidney, right lobe of thyroid gland, submandibular gland, testicle
RNA expression pattern · 19
CLCNKA → anterior pituitary, blastocyst, body of pancreas, body of stomach, connecting tubule, distal tubule, human kidney, inner renal medulla, inner stripe of outer renal medulla, left lobe of thyroid gland, morula, outer renal medulla, pituitary gland, right adrenal cortex, right hemisphere of cerebellum, right kidney, right lobe of thyroid gland, submandibular gland, testicle
Gene ontology · 17
CLCNKA → chloride channel activity, chloride channel complex, chloride transmembrane transport, chloride transport, excretion, identical protein binding, integral component of membrane, integral component of plasma membrane, ion transmembrane transport, ion transport, membrane, metal ion binding, plasma membrane, regulation of ion transmembrane transport, transmembrane transport, voltage-gated chloride channel activity, voltage-gated ion channel activity
related to Gene variants · 17
CLCNKA → African, Although, Arginine, ClC-Ka, ClC-Kb, CLCKNA, CLCNKB, Four SNPs, Glycine, HSPB7, Na, Of, SNP, SNPs, The CLCNKA, This, This SNP
related to External links · 8
CLCNKA → Human CLCNKA, Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, UCSC Genome Browser, United States National Library
Band · 2
CLCNKA → 1p36.13, 4|4 D3
Chr. · 2
CLCNKA → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
CLCNKA → 141,143,325 bp, 16,034,050 bp
Aliases · 1
CLCNKA → CLCNKA, CLCK1, ClC-K1, hClC-Ka, chloride voltage-gated channel Ka
Available structures · 1
CLCNKA → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2PFI

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene chloride channel human bp chr band protein heart chromosome location function salt snp clc-ka found snps voltage-gated end pathology

CLCNKA relationships Subject–Predicate–Object triples

TTTA extracted 104 structured relationships around CLCNKA. Examples in this analysis include CLCNKA → Aliases → CLCNKA, CLCK1, ClC-K1, hClC-Ka, chloride voltage-gated channel Ka and CLCNKA → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2PFI. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CLCNKAAliasesCLCNKA, CLCK1, ClC-K1, hClC-Ka, chloride voltage-gated channel Ka1.00infobox
CLCNKAAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2PFI1.00infobox
CLCNKABand1p36.131.00infobox
CLCNKABand4|4 D31.00infobox
CLCNKABgeeleft lobe of thyroid gland1.00infobox
CLCNKABgeeright lobe of thyroid gland1.00infobox
CLCNKABgeepituitary gland1.00infobox
CLCNKABgeeanterior pituitary1.00infobox
CLCNKABgeebody of pancreas1.00infobox
CLCNKABgeehuman kidney1.00infobox
CLCNKABgeeright adrenal cortex1.00infobox
CLCNKABgeetesticle1.00infobox
CLCNKABgeeright hemisphere of cerebellum1.00infobox
CLCNKABgeebody of stomach1.00infobox
CLCNKABgeeblastocyst1.00infobox
CLCNKABgeeright kidney1.00infobox
CLCNKABgeeinner renal medulla1.00infobox
CLCNKABgeeouter renal medulla1.00infobox
CLCNKABgeeinner stripe of outer renal medulla1.00infobox
CLCNKABgeesubmandibular gland1.00infobox
CLCNKABgeeconnecting tubule1.00infobox
CLCNKABgeedistal tubule1.00infobox
CLCNKABgeemorula1.00infobox
CLCNKABioGPSMore reference expression data1.00infobox
CLCNKAChr.Chromosome 1 (human)1.00infobox
CLCNKAChr.Chromosome 4 (mouse)1.00infobox
CLCNKADatabasesNCBI: entry; OMA: entry1.00infobox
CLCNKAEnd16,034,050 bp1.00infobox
CLCNKAEnd141,143,325 bp1.00infobox
CLCNKAEnsemblENSG000001865101.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CLCNKA bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CLCNKA
    • Gene
    • Protein
    • Human
    • Location
    • Search
    • Voltage-gated
    • Channels
    • Kidney
    • Pathology
    • Chromosome
    • Function
    • Bp
  • clcnka
    • Gene
    • Protein
    • Human
    • Location
    • Search
    • Voltage-gated
    • Channels
    • Kidney
    • Pathology
    • Chromosome
    • Function
    • Bp
  • chloride channels
    • Kidney
    • Clc-ka
    • Function
    • Clcnka
    • Channels
    • Chloride
    • Protein
    • Human
    • Mouse
    • Search
    • Voltage-gated
    • End
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Protein
    • Mouse
    • Search
    • Variants
    • Voltage-gated
    • End
    • Band
  • gene variants
    • Location
    • Human
    • Search
    • Voltage-gated
    • Chromosome
    • Bp
    • Chr
    • Protein
    • Mouse
    • Variants
    • End
    • Band
  • function
    • Search
    • Voltage-gated
    • Channels
    • Kidney
    • Chromosome
    • Location
    • Bp
    • Chr
    • External
    • Human
    • Mouse
    • Variants
  • pathology
    • Search
    • Variants
    • Voltage-gated
    • Blood
    • Increased
    • Pressure
    • Rate
    • Variant
    • Location
    • Heart
    • Human
  • protein
    • Search
    • Voltage-gated
    • Snp
    • Heart

Connections between topic areas Semantic bridges

For CLCNKA, one of the stronger structural bridges in this analysis connects CLCNKA with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CLCNKAFunction · splits 11 ⟂ 4
CLCNKAPathology · splits 11 ⟂ 4
CLCNKAOverview · splits 12 ⟂ 3
CLCNKAGene variants · splits 12 ⟂ 3

Map overview Semantic statistics

CLCNKA

Nodes15
Edges14
Triples104
Avg. degree1.87
Density0.133333
Components1

Source & methodology

TTTA analyzes the structure around CLCNKA to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Function & Pathology, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CLCNKA · EN edition · Analysis: TopicsToTalkAbout

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