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Probable cytosolic iron-sulfur protein assembly protein CIAO1 is a protein that in humans is encoded by the CIAO1 gene. CIAO1 forms a complex with FAM96B, MMS19, the co-chaperone HSC20 and the scaffold protein ISCU in order to assist iron-sulfur cluster incorporation into cytoplasmic and nuclear iron-sulfur proteins.
The analysis highlights Companies and Overview as prominent areas in the source structure around CIAO1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around CIAO1 shows recurring relationship patterns in the source. For example, CIAO1 → adrenal gland, body of pancreas, cerebellar hemisphere, dentate gyrus of hippocampal formation granule cell, ganglionic eminence, granulocyte, human kidney, interventricular septum, left adrenal cortex, lip, medial ganglionic eminence, muscle of thigh, nucleus accumbens, putamen, right adrenal cortex, right frontal lobe, right kidney, right ventricle, seminal vesicula, ventricular zone Another extracted example is CIAO1 → chromosome segregation, CIA complex, cytoplasm, iron-sulfur cluster assembly, MMXD complex, positive regulation of cell population proliferation, protein binding, protein maturation by iron-sulfur cluster transfer, regulation of transcription by RNA polymerase II. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp human gene chr band iron-sulfur protein chromosome location assembly mouse cytosolic complex cluster external component search 274 173 end
TTTA extracted 75 structured relationships around CIAO1. Examples in this analysis include CIAO1 → Aliases → CIAO1, CIA1, WDR39, cytosolic iron-sulfur assembly component 1 and CIAO1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3FM0. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CIAO1 | Aliases | CIAO1, CIA1, WDR39, cytosolic iron-sulfur assembly component 1 | 1.00 | infobox |
| CIAO1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3FM0 | 1.00 | infobox |
| CIAO1 | Band | 2q11.2 | 1.00 | infobox |
| CIAO1 | Band | 2 F1|2 61.86 cM | 1.00 | infobox |
| CIAO1 | Bgee | right adrenal cortex | 1.00 | infobox |
| CIAO1 | Bgee | left adrenal cortex | 1.00 | infobox |
| CIAO1 | Bgee | granulocyte | 1.00 | infobox |
| CIAO1 | Bgee | ganglionic eminence | 1.00 | infobox |
| CIAO1 | Bgee | cerebellar hemisphere | 1.00 | infobox |
| CIAO1 | Bgee | ventricular zone | 1.00 | infobox |
| CIAO1 | Bgee | body of pancreas | 1.00 | infobox |
| CIAO1 | Bgee | right frontal lobe | 1.00 | infobox |
| CIAO1 | Bgee | putamen | 1.00 | infobox |
| CIAO1 | Bgee | nucleus accumbens | 1.00 | infobox |
| CIAO1 | Bgee | right ventricle | 1.00 | infobox |
| CIAO1 | Bgee | right kidney | 1.00 | infobox |
| CIAO1 | Bgee | muscle of thigh | 1.00 | infobox |
| CIAO1 | Bgee | interventricular septum | 1.00 | infobox |
| CIAO1 | Bgee | medial ganglionic eminence | 1.00 | infobox |
| CIAO1 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| CIAO1 | Bgee | human kidney | 1.00 | infobox |
| CIAO1 | Bgee | lip | 1.00 | infobox |
| CIAO1 | Bgee | adrenal gland | 1.00 | infobox |
| CIAO1 | Bgee | seminal vesicula | 1.00 | infobox |
| CIAO1 | BioGPS | More reference expression data | 1.00 | infobox |
| CIAO1 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| CIAO1 | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| CIAO1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CIAO1 | End | 96,274,173 bp | 1.00 | infobox |
| CIAO1 | End | 127,089,736 bp | 1.00 | infobox |
The concept neighborhoods around CIAO1 bring nearby vocabulary together. In this analysis, examples include Iron-sulfur, Protein and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
Bridges highlight paths between different parts of the CIAO1 map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around CIAO1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Companies & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — CIAO1 · EN edition · Analysis: TopicsToTalkAbout