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Chaotropic agent

A chaotropic agent is a molecule in water solution that can disrupt the hydrogen bonding network between water molecules (i.e. exerts chaotropic activity). This has an effect on the stability of the native state of other molecules in the solution, mainly macromolecules (proteins, nucleic acids) by weakening the hydrophobic effect. For example, a…

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Chaotropic agent

Nodes44
Edges43
Triples18
Avg. degree1.95
Density0.045455
Components1

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Chaotropic agent

Top relations

related to overview · 7
Chaotropic agent → Chaotropic, DNA, Macromolecular, RNA, Tertiary, This, Waals
is a · 2
Chaotropic agent → molecule in water solution that can disrupt the hydrogen bonding network between water molecules, substance which disrupts the structure of

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Important terminology

chaotropic hydrophobic solution protein molecules salts agent water acids proteins hydrogen increase macromolecules forces bonding activity effect structure effects molecule

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Chaotropic agentis amolecule in water solution that can disrupt the hydrogen bonding network between water molecules0.90text
Chaotropic agentis asubstance which disrupts the structure of0.90text
ammonium sulphate can be used to precipitate substances from the impure mixtureinstance ofAntichaotropic salts0.80text
proteinsinstance ofmacromolecules0.80text
nucleic acidsinstance ofmacromolecules0.80text
hydrogen bondsinstance ofChaotropic solutes increase the entropy of the system by interfering with intermolecular interactions mediated by non-covalent forces0.80text
van der Waals forcesinstance ofChaotropic solutes increase the entropy of the system by interfering with intermolecular interactions mediated by non-covalent forces0.80text
and hydrophobic effectsinstance ofChaotropic solutes increase the entropy of the system by interfering with intermolecular interactions mediated by non-covalent forces0.80text
ethanol interfere with non-covalent intramolecular forces as outlined aboveinstance ofWhereas chaotropic compounds0.80text
salts can have chaotropic properties by shielding chargesinstance ofWhereas chaotropic compounds0.80text
preventing the stabilization of salt bridgesinstance ofWhereas chaotropic compounds0.80text
Chaotropic agentrelated to overviewDNA0.60section

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