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Cethromycin

Cethromycin, trade name Restanza (initially known as ABT-773) is a ketolide antibiotic undergoing research for the treatment of community acquired pneumonia (CAP) and for the prevention of post-exposure inhalational anthrax, and was given an "orphan drug" status for this indication. Originally discovered and developed by Abbott, it was acquired by…

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3D model (JSmol)
Interactive image
ATC code
none
Bioavailability
Between 35.8 and 60% in animal studies.
CAS Number
205110-48-1 Y
ChEBI
CHEBI:29506
ChEMBL
ChEMBL365528 N

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Overview

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Map overview Semantic statistics

Cethromycin

Nodes10
Edges9
Triples23
Avg. degree1.8
Density0.2
Components1

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Cethromycin

Top relations

related to Further reading · 5
Cethromycin → Human Polymorphonuclear Neutrophils, In Vitro, Interaction, New Ketolide ABT-773, Phagocytic Cell Line PLB-985
3D model (JSmol) · 1
Cethromycin → Interactive image
ATC code · 1
Cethromycin → none
Bioavailability · 1
Cethromycin → Between 35.8 and 60% in animal studies.
CAS Number · 1
Cethromycin → 205110-48-1 Y
ChEBI · 1
Cethromycin → CHEBI:29506
ChEMBL · 1
Cethromycin → ChEMBL365528 N
ChemSpider · 1
Cethromycin → 23258189 N
Elimination half-life · 1
Cethromycin → 1.6, 3.0, 4.5, 5.9 and 6 hours. Mouse, Monkey, Rat, Dog and Human respectively.
Excretion · 1
Cethromycin → 7.0% urine 87.2% faeces

Important terminology Word statistics

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Important terminology

acquired drug community pneumonia advanced life sciences fda new treatment 2008 application committee name status administration phase clinical ketolide abt-773

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cethromycin3D model (JSmol)Interactive image1.00infobox
CethromycinATC codenone1.00infobox
CethromycinBioavailabilityBetween 35.8 and 60% in animal studies.1.00infobox
CethromycinCAS Number205110-48-1 Y1.00infobox
CethromycinChEBICHEBI:295061.00infobox
CethromycinChEMBLChEMBL365528 N1.00infobox
CethromycinChemSpider23258189 N1.00infobox
CethromycinElimination half-life1.6, 3.0, 4.5, 5.9 and 6 hours. Mouse, Monkey, Rat, Dog and Human respectively.1.00infobox
CethromycinExcretion7.0% urine 87.2% faeces1.00infobox
CethromycinFormulaC42H59N3O101.00infobox
CethromycinKEGGD02391 N1.00infobox
CethromycinLegal statusUS: Phase III Clinical Trials1.00infobox
CethromycinMelting point211 to 213 °C (412 to 415 °F)1.00infobox
CethromycinMetabolismLiver1.00infobox
CethromycinMolar mass765.945 g·mol−11.00infobox
CethromycinPubChem CID52820451.00infobox
CethromycinRoutes of administrationOral1.00infobox
CethromycinUNIIJ0086219X61.00infobox

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