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CCL11

C-C motif chemokine 11 also known as eosinophil chemotactic protein and eotaxin-1 is a protein that in humans is encoded by the CCL11 gene. This gene is encoded on three exons and is located on chromosome 17.

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Aliases
CCL11, SCYA11, C-C motif chemokine ligand 11
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EOT, 2EOT, 2MPM
Band
17q12 · 11 C|11 49.84 cM
Bgee
pylorus · cardia · cecum · appendix · epithelium of colon
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

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Overview

Function

Clinical significance

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Map overview Semantic statistics

CCL11

Nodes25
Edges24
Triples124
Avg. degree1.92
Density0.08
Components1

How this topic connects Entity context

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CCL11

Top relations

Gene ontology · 47
CCL11 → actin filament organization, antimicrobial humoral immune response mediated by antimicrobial peptide, branching involved in mammary gland duct morphogenesis, CCR chemokine receptor binding, CCR3 chemokine receptor binding, cell adhesion, cellular calcium ion homeostasis, cellular response to interferon-gamma, cellular response to interleukin-1, cellular response to tumor necrosis factor, chemokine activity, chemokine-mediated signaling pathway, chemotaxis, chronic inflammatory response, cytokine activity, cytokine-mediated signaling pathway, cytoskeleton organization, eosinophil chemotaxis, ERK1 and ERK2 cascade, extracellular region
Bgee · 20
CCL11 → appendix, cardia, cecum, cervix, duodenum, epithelium of colon, fundus, intercostal muscle, lip, lumbar spinal ganglion, medial head of gastrocnemius muscle, migratory enteric neural crest cell, mucosa of transverse colon, muscle layer of sigmoid colon, muscle of thigh, pylorus, right ventricle, sciatic nerve, tunica adventitia of aorta, white adipose tissue
RNA expression pattern · 20
CCL11 → appendix, cardia, cecum, cervix, duodenum, epithelium of colon, fundus, intercostal muscle, lip, lumbar spinal ganglion, medial head of gastrocnemius muscle, migratory enteric neural crest cell, mucosa of transverse colon, muscle layer of sigmoid colon, muscle of thigh, pylorus, right ventricle, sciatic nerve, tunica adventitia of aorta, white adipose tissue
related to Function · 8
CCL11 → CC, CCR2, CCR3, CCR5, Chemokine, G-protein-linked, However, The
related to Clinical significance · 3
CCL11 → Additionally, Higher, Increased CCL11
Band · 2
CCL11 → 11 C|11 49.84 cM, 17q12
Chr. · 2
CCL11 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
CCL11 → 34,288,334 bp, 81,953,781 bp
related to External links · 2
CCL11 → Human CCL11, UCSC Genome Browser
Aliases · 1
CCL11 → CCL11, SCYA11, C-C motif chemokine ligand 11

Important terminology Word statistics

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Important terminology

gene chemokine bp human chromosome 17 chr band 11 location ccr3 ligand also known encoded protein mouse receptor c-c motif

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CCL11AliasesCCL11, SCYA11, C-C motif chemokine ligand 111.00infobox
CCL11Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EOT, 2EOT, 2MPM1.00infobox
CCL11Band17q121.00infobox
CCL11Band11 C|11 49.84 cM1.00infobox
CCL11Bgeepylorus1.00infobox
CCL11Bgeecardia1.00infobox
CCL11Bgeececum1.00infobox
CCL11Bgeeappendix1.00infobox
CCL11Bgeeepithelium of colon1.00infobox
CCL11Bgeemuscle layer of sigmoid colon1.00infobox
CCL11Bgeeright ventricle1.00infobox
CCL11Bgeefundus1.00infobox
CCL11Bgeeduodenum1.00infobox
CCL11Bgeemucosa of transverse colon1.00infobox
CCL11Bgeecervix1.00infobox
CCL11Bgeelumbar spinal ganglion1.00infobox
CCL11Bgeeintercostal muscle1.00infobox
CCL11Bgeemigratory enteric neural crest cell1.00infobox
CCL11Bgeesciatic nerve1.00infobox
CCL11Bgeewhite adipose tissue1.00infobox
CCL11Bgeemuscle of thigh1.00infobox
CCL11Bgeetunica adventitia of aorta1.00infobox
CCL11Bgeelip1.00infobox
CCL11Bgeemedial head of gastrocnemius muscle1.00infobox
CCL11BioGPSMore reference expression data1.00infobox
CCL11Chr.Chromosome 17 (human)1.00infobox
CCL11Chr.Chromosome 11 (mouse)1.00infobox
CCL11DatabasesNCBI: entry; OMA: entry1.00infobox
CCL11End34,288,334 bp1.00infobox
CCL11End81,953,781 bp1.00infobox

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