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C-C motif chemokine 11 also known as eosinophil chemotactic protein and eotaxin-1 is a protein that in humans is encoded by the CCL11 gene. This gene is encoded on three exons and is located on chromosome 17.
The analysis highlights Function, Clinical significance and Overview as prominent areas in the source structure around CCL11.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around CCL11 shows recurring relationship patterns in the source. For example, CCL11 → actin filament organization, antimicrobial humoral immune response mediated by antimicrobial peptide, branching involved in mammary gland duct morphogenesis, CCR chemokine receptor binding, CCR3 chemokine receptor binding, cell adhesion, cellular calcium ion homeostasis, cellular response to interferon-gamma, cellular response to interleukin-1, cellular response to tumor necrosis factor, chemokine activity, chemokine-mediated signaling pathway, chemotaxis, chronic inflammatory response, cytokine activity, cytokine-mediated signaling pathway, cytoskeleton organization, eosinophil chemotaxis, ERK1 and ERK2 cascade, extracellular region Another extracted example is CCL11 → appendix, cardia, cecum, cervix, duodenum, epithelium of colon, fundus, intercostal muscle, lip, lumbar spinal ganglion, medial head of gastrocnemius muscle, migratory enteric neural crest cell, mucosa of transverse colon, muscle layer of sigmoid colon, muscle of thigh, pylorus, right ventricle, sciatic nerve, tunica adventitia of aorta, white adipose tissue. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene chemokine bp human chromosome 17 chr band 11 location ccr3 ligand also known encoded protein mouse receptor c-c motif
TTTA extracted 124 structured relationships around CCL11. Examples in this analysis include CCL11 → Aliases → CCL11, SCYA11, C-C motif chemokine ligand 11 and CCL11 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EOT, 2EOT, 2MPM. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CCL11 | Aliases | CCL11, SCYA11, C-C motif chemokine ligand 11 | 1.00 | infobox |
| CCL11 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EOT, 2EOT, 2MPM | 1.00 | infobox |
| CCL11 | Band | 17q12 | 1.00 | infobox |
| CCL11 | Band | 11 C|11 49.84 cM | 1.00 | infobox |
| CCL11 | Bgee | pylorus | 1.00 | infobox |
| CCL11 | Bgee | cardia | 1.00 | infobox |
| CCL11 | Bgee | cecum | 1.00 | infobox |
| CCL11 | Bgee | appendix | 1.00 | infobox |
| CCL11 | Bgee | epithelium of colon | 1.00 | infobox |
| CCL11 | Bgee | muscle layer of sigmoid colon | 1.00 | infobox |
| CCL11 | Bgee | right ventricle | 1.00 | infobox |
| CCL11 | Bgee | fundus | 1.00 | infobox |
| CCL11 | Bgee | duodenum | 1.00 | infobox |
| CCL11 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| CCL11 | Bgee | cervix | 1.00 | infobox |
| CCL11 | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| CCL11 | Bgee | intercostal muscle | 1.00 | infobox |
| CCL11 | Bgee | migratory enteric neural crest cell | 1.00 | infobox |
| CCL11 | Bgee | sciatic nerve | 1.00 | infobox |
| CCL11 | Bgee | white adipose tissue | 1.00 | infobox |
| CCL11 | Bgee | muscle of thigh | 1.00 | infobox |
| CCL11 | Bgee | tunica adventitia of aorta | 1.00 | infobox |
| CCL11 | Bgee | lip | 1.00 | infobox |
| CCL11 | Bgee | medial head of gastrocnemius muscle | 1.00 | infobox |
| CCL11 | BioGPS | More reference expression data | 1.00 | infobox |
| CCL11 | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| CCL11 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| CCL11 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CCL11 | End | 34,288,334 bp | 1.00 | infobox |
| CCL11 | End | 81,953,781 bp | 1.00 | infobox |
The concept neighborhoods around CCL11 bring nearby vocabulary together. In this analysis, examples include Chemokine, Ccr3 and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For CCL11, one of the stronger structural bridges in this analysis connects CCL11 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around CCL11 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — CCL11 · EN edition · Analysis: TopicsToTalkAbout