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CASPR: Art, Function & Clinical

CASPR also known as Contactin associated protein 1, Paranodin and CASPR1 is a protein that in humans is encoded by the CNTNAP1 gene. CASPR is a part of the neurexin family of proteins, hence its another name "Neurexin IV". CASPR is a membrane protein found in the neuronal membrane in the paranodal section of the axon] in myelinated neurons, between the…

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CASPR topic overview

The analysis highlights Art, Function and Clinical as prominent areas in the source structure around CASPR.

Related topics
11
Source areas
3
Connected nodes
14
Extracted relationships
91
Related term clusters
9
Bridge connections
14

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 5 topics
Function · 4 topics
Clinical · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CNTNAP1, CASPR, CNTNAP, NRXN4, P190, contactin associated protein 1, CHN3
Band
17q21.2 · 11|11 D
Bgee
right hemisphere of cerebellum · Region I of hippocampus proper · postcentral gyrus · right frontal lobe · Brodmann area 46
BioGPS
n/a
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How CASPR connects Entity context

The extracted context around CASPR shows recurring relationship patterns in the source. For example, CASPR → axon, cell adhesion, cell junction, central nervous system myelination, cytoskeleton organization, integral component of membrane, integral component of plasma membrane, membrane, myelin sheath, myelination in peripheral nervous system, neuromuscular process controlling balance, neuromuscular process controlling posture, neuron projection development, neuron projection morphogenesis, neuronal action potential propagation, paranodal junction, paranodal junction assembly, paranode region of axon, positive regulation of signal transduction, presynaptic active zone membrane Another extracted example is CASPR → Brodmann area 46, Brodmann area 9, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, neural layer of retina, orbitofrontal cortex, perirhinal cortex, postcentral gyrus, prefrontal cortex, primary visual cortex, Region I of hippocampus proper, right frontal lobe, right hemisphere of cerebellum, secondary oocyte, superior frontal gyrus, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

CASPR

Top relations

Gene ontology · 27
CASPR → axon, cell adhesion, cell junction, central nervous system myelination, cytoskeleton organization, integral component of membrane, integral component of plasma membrane, membrane, myelin sheath, myelination in peripheral nervous system, neuromuscular process controlling balance, neuromuscular process controlling posture, neuron projection development, neuron projection morphogenesis, neuronal action potential propagation, paranodal junction, paranodal junction assembly, paranode region of axon, positive regulation of signal transduction, presynaptic active zone membrane
Bgee · 19
CASPR → Brodmann area 46, Brodmann area 9, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, neural layer of retina, orbitofrontal cortex, perirhinal cortex, postcentral gyrus, prefrontal cortex, primary visual cortex, Region I of hippocampus proper, right frontal lobe, right hemisphere of cerebellum, secondary oocyte, superior frontal gyrus, zygote
RNA expression pattern · 19
CASPR → Brodmann area 46, Brodmann area 9, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, neural layer of retina, orbitofrontal cortex, perirhinal cortex, postcentral gyrus, prefrontal cortex, primary visual cortex, Region I of hippocampus proper, right frontal lobe, right hemisphere of cerebellum, secondary oocyte, superior frontal gyrus, zygote
related to Function · 4
CASPR → Jan, Northern, PTPRZ1, RefSeq
Band · 2
CASPR → 11|11 D, 17q21.2
Chr. · 2
CASPR → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
CASPR → 101,081,550 bp, 42,699,993 bp
is a · 2
CASPR → membrane protein found in the neuronal membrane in the paranodal section of the axon, part of the neurexin family of proteins
Aliases · 1
CASPR → CNTNAP1, CASPR, CNTNAP, NRXN4, P190, contactin associated protein 1, CHN3
BioGPS · 1
CASPR → n/a

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene protein bp cntnap1 human chr band contactin chromosome 17 associated location domain complex membrane paranodal axon juxtaparanode mouse neuronal

CASPR relationships Subject–Predicate–Object triples

TTTA extracted 91 structured relationships around CASPR. Examples in this analysis include CASPR → Aliases → CNTNAP1, CASPR, CNTNAP, NRXN4, P190, contactin associated protein 1, CHN3 and CASPR → Band → 17q21.2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CASPRAliasesCNTNAP1, CASPR, CNTNAP, NRXN4, P190, contactin associated protein 1, CHN31.00infobox
CASPRBand17q21.21.00infobox
CASPRBand11|11 D1.00infobox
CASPRBgeeright hemisphere of cerebellum1.00infobox
CASPRBgeeRegion I of hippocampus proper1.00infobox
CASPRBgeepostcentral gyrus1.00infobox
CASPRBgeeright frontal lobe1.00infobox
CASPRBgeeBrodmann area 461.00infobox
CASPRBgeesuperior frontal gyrus1.00infobox
CASPRBgeeorbitofrontal cortex1.00infobox
CASPRBgeelateral nuclear group of thalamus1.00infobox
CASPRBgeeprefrontal cortex1.00infobox
CASPRBgeeBrodmann area 91.00infobox
CASPRBgeedentate gyrus of hippocampal formation granule cell1.00infobox
CASPRBgeeprimary visual cortex1.00infobox
CASPRBgeecerebellar cortex1.00infobox
CASPRBgeeneural layer of retina1.00infobox
CASPRBgeezygote1.00infobox
CASPRBgeelumbar subsegment of spinal cord1.00infobox
CASPRBgeeperirhinal cortex1.00infobox
CASPRBgeesecondary oocyte1.00infobox
CASPRBgeeentorhinal cortex1.00infobox
CASPRBioGPSn/a1.00infobox
CASPRChr.Chromosome 17 (human)1.00infobox
CASPRChr.Chromosome 11 (mouse)1.00infobox
CASPRDatabasesNCBI: entry; OMA: entry1.00infobox
CASPREnd42,699,993 bp1.00infobox
CASPREnd101,081,550 bp1.00infobox
CASPREnsemblENSG000001087971.00infobox
CASPREntrez85061.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around CASPR bring nearby vocabulary together. In this analysis, examples include Protein, Contactin and P190. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CASPR
    • Protein
    • Contactin
    • P190
    • Associated
    • Cntnap1
    • Gene
    • External
    • Myelinated
    • Neurexin
    • Axon
    • Complex
    • Function
  • caspr
    • Protein
    • Contactin
    • P190
    • Associated
    • Cntnap1
    • Gene
    • External
    • Myelinated
    • Neurexin
    • Axon
    • Complex
    • Function
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Protein
    • End
    • Expression
    • Function
    • Mouse
    • Ucsc
    • Band
  • juxtaparanode
    • Membrane
    • Neuronal
    • Paranodal
    • Myelinated
    • Complex
    • End
    • Expression
    • Function
    • Mouse
    • Myelination
    • Neurons
    • Protein
  • function
    • Chromosome
    • Location
    • Bp
    • Chr
    • Human
    • End
    • Expression
    • Juxtaparanode
    • Membrane
    • Mouse
    • Myelination
    • Neuronal
  • paranodal
    • Myelinated
    • Complex
    • End
    • Expression
    • Function
    • Mouse
    • Myelination
    • Neurons
    • Protein
    • Refseq
    • Signaling
    • Ucsc
  • protein
    • Refseq
    • Signaling
    • Myelination
    • Ucsc
  • myelinated
    • Neuronal
    • Neurons
    • Paranodal
    • Protein

Connections between topic areas Semantic bridges

For CASPR, one of the stronger structural bridges in this analysis connects CASPR with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CASPR — Overview · splits 9 ⟂ 6
CASPR — Function · splits 10 ⟂ 5
CASPR — Clinical · splits 12 ⟂ 3

Map overview Semantic statistics

CASPR

Nodes15
Edges14
Triples91
Avg. degree1.87
Density0.133333
Components1

Source & methodology

TTTA analyzes the structure around CASPR to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Function & Clinical, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CASPR · EN edition · Analysis: TopicsToTalkAbout

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