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CASPR also known as Contactin associated protein 1, Paranodin and CASPR1 is a protein that in humans is encoded by the CNTNAP1 gene. CASPR is a part of the neurexin family of proteins, hence its another name "Neurexin IV". CASPR is a membrane protein found in the neuronal membrane in the paranodal section of the axon] in myelinated neurons, between the…
The analysis highlights Art, Function and Clinical as prominent areas in the source structure around CASPR.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around CASPR shows recurring relationship patterns in the source. For example, CASPR → axon, cell adhesion, cell junction, central nervous system myelination, cytoskeleton organization, integral component of membrane, integral component of plasma membrane, membrane, myelin sheath, myelination in peripheral nervous system, neuromuscular process controlling balance, neuromuscular process controlling posture, neuron projection development, neuron projection morphogenesis, neuronal action potential propagation, paranodal junction, paranodal junction assembly, paranode region of axon, positive regulation of signal transduction, presynaptic active zone membrane Another extracted example is CASPR → Brodmann area 46, Brodmann area 9, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, neural layer of retina, orbitofrontal cortex, perirhinal cortex, postcentral gyrus, prefrontal cortex, primary visual cortex, Region I of hippocampus proper, right frontal lobe, right hemisphere of cerebellum, secondary oocyte, superior frontal gyrus, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
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gene protein bp cntnap1 human chr band contactin chromosome 17 associated location domain complex membrane paranodal axon juxtaparanode mouse neuronal
TTTA extracted 91 structured relationships around CASPR. Examples in this analysis include CASPR → Aliases → CNTNAP1, CASPR, CNTNAP, NRXN4, P190, contactin associated protein 1, CHN3 and CASPR → Band → 17q21.2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CASPR | Aliases | CNTNAP1, CASPR, CNTNAP, NRXN4, P190, contactin associated protein 1, CHN3 | 1.00 | infobox |
| CASPR | Band | 17q21.2 | 1.00 | infobox |
| CASPR | Band | 11|11 D | 1.00 | infobox |
| CASPR | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| CASPR | Bgee | Region I of hippocampus proper | 1.00 | infobox |
| CASPR | Bgee | postcentral gyrus | 1.00 | infobox |
| CASPR | Bgee | right frontal lobe | 1.00 | infobox |
| CASPR | Bgee | Brodmann area 46 | 1.00 | infobox |
| CASPR | Bgee | superior frontal gyrus | 1.00 | infobox |
| CASPR | Bgee | orbitofrontal cortex | 1.00 | infobox |
| CASPR | Bgee | lateral nuclear group of thalamus | 1.00 | infobox |
| CASPR | Bgee | prefrontal cortex | 1.00 | infobox |
| CASPR | Bgee | Brodmann area 9 | 1.00 | infobox |
| CASPR | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| CASPR | Bgee | primary visual cortex | 1.00 | infobox |
| CASPR | Bgee | cerebellar cortex | 1.00 | infobox |
| CASPR | Bgee | neural layer of retina | 1.00 | infobox |
| CASPR | Bgee | zygote | 1.00 | infobox |
| CASPR | Bgee | lumbar subsegment of spinal cord | 1.00 | infobox |
| CASPR | Bgee | perirhinal cortex | 1.00 | infobox |
| CASPR | Bgee | secondary oocyte | 1.00 | infobox |
| CASPR | Bgee | entorhinal cortex | 1.00 | infobox |
| CASPR | BioGPS | n/a | 1.00 | infobox |
| CASPR | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| CASPR | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| CASPR | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CASPR | End | 42,699,993 bp | 1.00 | infobox |
| CASPR | End | 101,081,550 bp | 1.00 | infobox |
| CASPR | Ensembl | ENSG00000108797 | 1.00 | infobox |
| CASPR | Entrez | 8506 | 1.00 | infobox |
The concept neighborhoods around CASPR bring nearby vocabulary together. In this analysis, examples include Protein, Contactin and P190. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For CASPR, one of the stronger structural bridges in this analysis connects CASPR with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around CASPR to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Function & Clinical, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — CASPR · EN edition · Analysis: TopicsToTalkAbout