Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

C4A: Regions, Function & Overview

Complement C4-A is a kind of the Complement component 4 protein that in humans is encoded by the C4A gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

C4A topic overview

The analysis highlights Regions, Function and Overview as prominent areas in the source structure around C4A.

Related topics
11
Source areas
2
Connected nodes
13
Extracted relationships
102
Concept neighborhoods
7
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 8 topics
Overview · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
C4A, C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG, complement component 4A (Rodgers blood group), complement C4A (Rodgers blood group)
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HZF, 4FXG, 4FXK, 4XAM
Band
6p21.33 · 17 B1|17 18.29 cM
Bgee
right lobe of liver · right adrenal cortex · left adrenal cortex · right lobe of thyroid gland · left lobe of thyroid gland
BioGPS
More reference expression data
Chr.
Chromosome 6 (human) · Chromosome 17 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How C4A connects Entity context

The extracted context around C4A shows recurring relationship patterns in the source. For example, C4A → axon, blood microparticle, cell junction, cell projection, complement activation, complement activation, classical pathway, complement component C1q complex binding, dendrite, endopeptidase inhibitor activity, endoplasmic reticulum lumen, extracellular exosome, extracellular region, extracellular space, immune system process, inflammatory response, innate immune response, negative regulation of endopeptidase activity, plasma membrane, positive regulation of apoptotic cell clearance, post-translational protein modification Another extracted example is C4A → adrenal gland, ankle joint, anterior pituitary, esophagus, left adrenal cortex, left lobe of thyroid gland, left ovary, liver, right adrenal cortex, right lobe of liver, right lobe of thyroid gland, right ovary, spleen, synovial joint, tibial nerve, urinary bladder, uterus, white adipose tissue, zone of skin. Use these groups to spot repeated connection types before inspecting the individual relationships.

C4A

Top relations

Gene ontology · 25
C4A → axon, blood microparticle, cell junction, cell projection, complement activation, complement activation, classical pathway, complement component C1q complex binding, dendrite, endopeptidase inhibitor activity, endoplasmic reticulum lumen, extracellular exosome, extracellular region, extracellular space, immune system process, inflammatory response, innate immune response, negative regulation of endopeptidase activity, plasma membrane, positive regulation of apoptotic cell clearance, post-translational protein modification
Bgee · 19
C4A → adrenal gland, ankle joint, anterior pituitary, esophagus, left adrenal cortex, left lobe of thyroid gland, left ovary, liver, right adrenal cortex, right lobe of liver, right lobe of thyroid gland, right ovary, spleen, synovial joint, tibial nerve, urinary bladder, uterus, white adipose tissue, zone of skin
RNA expression pattern · 19
C4A → adrenal gland, ankle joint, anterior pituitary, esophagus, left adrenal cortex, left lobe of thyroid gland, left ovary, liver, right adrenal cortex, right lobe of liver, right lobe of thyroid gland, right ovary, spleen, synovial joint, tibial nerve, urinary bladder, uterus, white adipose tissue, zone of skin
related to Function · 12
C4A → C4, C4B, Deficiency, Each, Excess, HERV-K, III, MHC, RCCX, The, This, Varying
related to External links · 4
C4A → Media, UCSC Genome Browser, Wikimedia CommonsHuman C4A, Wiktionary-logo-en-v2
Band · 2
C4A → 17 B1|17 18.29 cM, 6p21.33
Chr. · 2
C4A → Chromosome 17 (mouse), Chromosome 6 (human)
End · 2
C4A → 32,002,681 bp, 34,962,856 bp
Aliases · 1
C4A → C4A, C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG, complement component 4A (Rodgers blood group), complement C4A (Rodgers blood group)
Available structures · 1
C4A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HZF, 4FXG, 4FXK, 4XAM

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp human complement chr band chromosome component protein location mouse c4 complex function external blood search 002 681 end

C4A relationships Subject–Predicate–Object triples

TTTA extracted 102 structured relationships around C4A. Examples in this analysis include C4A → Aliases → C4A, C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG, complement component 4A (Rodgers blood group), complement C4A (Rodgers blood group) and C4A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HZF, 4FXG, 4FXK, 4XAM. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
C4AAliasesC4A, C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG, complement component 4A (Rodgers blood group), complement C4A (Rodgers blood group)1.00infobox
C4AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HZF, 4FXG, 4FXK, 4XAM1.00infobox
C4ABand6p21.331.00infobox
C4ABand17 B1|17 18.29 cM1.00infobox
C4ABgeeright lobe of liver1.00infobox
C4ABgeeright adrenal cortex1.00infobox
C4ABgeeleft adrenal cortex1.00infobox
C4ABgeeright lobe of thyroid gland1.00infobox
C4ABgeeleft lobe of thyroid gland1.00infobox
C4ABgeeright ovary1.00infobox
C4ABgeetibial nerve1.00infobox
C4ABgeeleft ovary1.00infobox
C4ABgeeanterior pituitary1.00infobox
C4ABgeespleen1.00infobox
C4ABgeezone of skin1.00infobox
C4ABgeeadrenal gland1.00infobox
C4ABgeewhite adipose tissue1.00infobox
C4ABgeesynovial joint1.00infobox
C4ABgeeankle joint1.00infobox
C4ABgeeliver1.00infobox
C4ABgeeuterus1.00infobox
C4ABgeeesophagus1.00infobox
C4ABgeeurinary bladder1.00infobox
C4ABioGPSMore reference expression data1.00infobox
C4AChr.Chromosome 6 (human)1.00infobox
C4AChr.Chromosome 17 (mouse)1.00infobox
C4ADatabasesNCBI: entry; OMA: entry1.00infobox
C4AEnd32,002,681 bp1.00infobox
C4AEnd34,962,856 bp1.00infobox
C4AEnsemblENSG00000244207 ENSG00000206340 ENSG00000244731 ENSG000002277461.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around C4A bring nearby vocabulary together. In this analysis, examples include Component, Complement and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • C4A
    • Component
    • Complement
    • Gene
    • Location
    • Human
    • Blood
    • Function
    • Search
    • System
    • Ucsc
    • Protein
    • Bp
  • c4a
    • Component
    • Complement
    • Gene
    • Location
    • Human
    • Blood
    • Function
    • Search
    • System
    • Ucsc
    • Protein
    • Bp
  • complement component 4
    • Component
    • C4a
    • Location
    • Blood
    • Function
    • Human
    • Search
    • System
    • Ucsc
    • Gene
    • Complex
    • Protein
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • B1
    • Blood
    • End
    • Function
    • Mouse
    • Region
    • Search
  • function
    • Search
    • Activation
    • Classical
    • Location
    • Pathway
    • Bp
    • Chr
    • Chromosome
    • Human
    • B1
    • End
    • Expressed
  • histocompatibility complex (mhc) class iii
    • Region
    • Classical
    • Pathway
    • End
    • Expressed
    • Function
    • Mouse
    • Search
    • System
    • Trimer
    • Ucsc
    • Gene
  • protein
    • Alpha
    • Chain
    • Cleaved
    • Region
    • Search
    • System
    • Trimer
    • Ucsc

Connections between topic areas Semantic bridges

For C4A, one of the stronger structural bridges in this analysis connects C4A with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
C4AFunction · splits 5 ⟂ 9
C4AOverview · splits 10 ⟂ 4

Map overview Semantic statistics

C4A

Nodes14
Edges13
Triples102
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around C4A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — C4A · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.