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Buehler test

The Buehler test is an in vivo test to screen for substances that cause human skin sensitisation (i.e. allergens). It was first proposed by Edwin Vernon Buehler in 1965 and further explained in 1980. The methods are described in OECD Test Guideline 406 and the US Environmental Protection Agency (USEPA) OSCPP 870.2600.

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In vivoAllergensAdjuvant
3 related topics

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Buehler test

Nodes5
Edges4
Triples1
Avg. degree1.6
Density0.4
Components1

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Buehler test

Top relations

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Buehler test → in vivo test to screen for substances that cause human skin sensitisation

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Important terminology

test group control challenge positive buehler skin highest following exposure response animals severity responses cause guinea pigs irritation sensitization system

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SubjectPredicateObjectConfidenceSrc
Buehler testis ain vivo test to screen for substances that cause human skin sensitisation0.90text

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