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Brimonidine

Brimonidine is an α2 agonist medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. In rosacea it improves the redness. It is used as eye drops or applied to the skin. It is also available in the fixed-dose combination medication brimonidine/timolol along with timolol maleate.

Applications, Overview & Medical uses

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Overview

Α2MedicationOpen-angle glaucomaOcular hypertensionRosacea
14 related topics

Medical uses

IndicatedIntraocular pressureCochrane
3 related topics

Mechanism of action

Adrenergic agonistClonidine
2 related topics

Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
D11AX21 (WHO) S01EA05 (WHO), S01EA55 (WHO), S01GA07 (WHO)
CAS Number
59803-98-4 Y
ChEBI
CHEBI:3175 Y
ChEMBL
ChEMBL844 Y

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Overview

Medical uses

Mechanism of action

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Map overview Semantic statistics

Brimonidine

Nodes23
Edges22
Triples42
Avg. degree1.91
Density0.086957
Components1

How this topic connects Entity context

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Brimonidine

Top relations

related to Further reading · 8
Brimonidine → Chen JL, Dikopf MS, Expert Opin Pharmacother, January, Oh DJ, PMID, S2CID, Vajaranant TS
related to Mechanism of action · 3
Brimonidine → Peripheral, The, This
related to Medical uses · 3
Brimonidine → Cochrane, It, The
Legal status · 2
Brimonidine → AU: S4 (Prescription only) / Schedule 2, US: ℞-only / OTC
3D model (JSmol) · 1
Brimonidine → Interactive image
AHFS/Drugs.com · 1
Brimonidine → Monograph
ATC code · 1
Brimonidine → D11AX21 (WHO) S01EA05 (WHO), S01EA55 (WHO), S01GA07 (WHO)
CAS Number · 1
Brimonidine → 59803-98-4 Y
ChEBI · 1
Brimonidine → CHEBI:3175 Y
ChEMBL · 1
Brimonidine → ChEMBL844 Y

Important terminology Word statistics

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Important terminology

medication used redness applied skin side effects include rosacea may eye blood use α2 ocular names agonist glaucoma available common

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Brimonidine3D model (JSmol)Interactive image1.00infobox
BrimonidineAHFS/Drugs.comMonograph1.00infobox
BrimonidineATC codeD11AX21 (WHO) S01EA05 (WHO), S01EA55 (WHO), S01GA07 (WHO)1.00infobox
BrimonidineCAS Number59803-98-4 Y1.00infobox
BrimonidineChEBICHEBI:3175 Y1.00infobox
BrimonidineChEMBLChEMBL844 Y1.00infobox
BrimonidineChemSpider2341 Y1.00infobox
BrimonidineCompTox Dashboard (EPA)DTXSID30452211.00infobox
BrimonidineDrugBankDB00484 Y1.00infobox
BrimonidineECHA InfoCard100.149.0421.00infobox
BrimonidineElimination half-life3 hours (ocular), 12 hours (topical)1.00infobox
BrimonidineFormulaC11H10BrN51.00infobox
BrimonidineIUPHAR/BPS5201.00infobox
BrimonidineKEGGD07540 Y1.00infobox
BrimonidineLegal statusAU: S4 (Prescription only) / Schedule 21.00infobox
BrimonidineLegal statusUS: ℞-only / OTC1.00infobox
BrimonidineLicense dataUS DailyMed: Brimonidine1.00infobox
BrimonidineMedlinePlusa6012321.00infobox
BrimonidineMelting point252 °C (486 °F)1.00infobox
BrimonidineMetabolismPrimarily liver1.00infobox
BrimonidineMolar mass292.140 g·mol−11.00infobox
BrimonidinePregnancy categoryAU: B31.00infobox
BrimonidinePronunciation/brɪˈmoʊnɪdiːn/ bri-MOH-nid-een1.00infobox
BrimonidinePubChem CID24351.00infobox
BrimonidineRoutes of administrationTopical1.00infobox
BrimonidineTrade namesAlphagan, Mirvaso, Lumify, others1.00infobox
BrimonidineUNIIE6GNX3HHTE1.00infobox
Brimonidineis aα2 agonist medication used to treat open-angle glaucoma0.90text

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