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The Bentley compounds are a class of semi-synthetic opioids that were first synthesized by K. W. Bentley by Diels-Alder reaction of thebaine with various dienophiles. The compounds are also known as thevinols, orvinols, or bridged oripavine derivatives, due to the characteristic 6,14-endo-ethano- or etheno-bridge and substitution at the 7α position.…
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compounds bentley first known also bridged oripavine derivatives thebaine dienophiles buprenorphine etorphine μ-opioid class semi-synthetic opioids synthesized diels-alder reaction various
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