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B4GALT7: Clinical significance, Function & Overview
Beta-1,4-galactosyltransferase 7 also known as galactosyltransferase I is an enzyme that in humans is encoded by the B4GALT7 gene. Galactosyltransferase I catalyzes the synthesis of the glycosaminoglycan-protein linkage in proteoglycans. Proteoglycans in turn are structural components of the extracellular matrix that is found between cells in connective…
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B4GALT7 topic overview
The analysis highlights Clinical significance, Function and Overview as prominent areas in the source structure around B4GALT7.
Related topics
24
Source areas
3
Connected nodes
27
Extracted relationships
100
Concept neighborhoods
14
Bridge connections
27
What this topic covers Research coverage
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Clinical significance · 9 topics
Function · 8 topics
Overview · 7 topics
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4IRP, 4IRQ
Band
5q35.3 · 13|13 B1
Bgee
tendon of biceps brachii · right adrenal gland · left adrenal gland · left adrenal cortex · right adrenal cortex
BioGPS
More reference expression data
Explore all related topics Closing gaps
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
How B4GALT7 connects Entity context
Entity context groups extracted connections by relationship type. Counts show recurrence in the analyzed source; the examples are research signals, not claims about importance.
The extracted context around B4GALT7 shows recurring relationship patterns in the source. For example, B4GALT7 → beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, carbohydrate metabolic process, galactosyltransferase activity, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, glycosyltransferase activity, Golgi apparatus, Golgi cisterna membrane, Golgi membrane, integral component of membrane, manganese ion binding, membrane, metal ion binding, negative regulation of fibroblast proliferation, protein binding, protein glycosylation, protein N-linked glycosylation, proteoglycan metabolic process, supramolecular fiber organization, transferase activity Another extracted example is B4GALT7 → anterior pituitary, apex of heart, blood, body of pancreas, body of stomach, cumulus cell, decidua, granulocyte, internal carotid artery, left adrenal cortex, left adrenal gland, medullary collecting duct, otic placode, otic vesicle, renal corpuscle, right adrenal cortex, right adrenal gland, saccule, stromal cell of endometrium, tendon of biceps brachii. Use these groups to spot repeated connection types before inspecting the individual relationships.
B4GALT7
Top relations
Gene ontology· 21
B4GALT7 → beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, carbohydrate metabolic process, galactosyltransferase activity, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, glycosyltransferase activity, Golgi apparatus, Golgi cisterna membrane, Golgi membrane, integral component of membrane, manganese ion binding, membrane, metal ion binding, negative regulation of fibroblast proliferation, protein binding, protein glycosylation, protein N-linked glycosylation, proteoglycan metabolic process, supramolecular fiber organization, transferase activity
Bgee· 20
B4GALT7 → anterior pituitary, apex of heart, blood, body of pancreas, body of stomach, cumulus cell, decidua, granulocyte, internal carotid artery, left adrenal cortex, left adrenal gland, medullary collecting duct, otic placode, otic vesicle, renal corpuscle, right adrenal cortex, right adrenal gland, saccule, stromal cell of endometrium, tendon of biceps brachii
RNA expression pattern· 20
B4GALT7 → anterior pituitary, apex of heart, blood, body of pancreas, body of stomach, cumulus cell, decidua, granulocyte, internal carotid artery, left adrenal cortex, left adrenal gland, medullary collecting duct, otic placode, otic vesicle, renal corpuscle, right adrenal cortex, right adrenal gland, saccule, stromal cell of endometrium, tendon of biceps brachii
related to Clinical significance· 8
B4GALT7 → CDG, Danlos, Ehlers, Larsen, Mutations, Since, Spondylodysplastic, The
related to External links· 5
B4GALT7 → Human B4GALT7, Human Beta-1, PDB, PDBe-KB, UCSC Genome Browser
Relationships are represented as Subject → Predicate → Object triples. Confidence describes extraction strength, not the real-world importance of a relationship; lower-confidence rows may be contextual rather than explicit.
TTTA extracted 100 structured relationships around B4GALT7. Examples in this analysis include B4GALT7 → 2.4.1.133 → ↗ and B4GALT7 → Aliases → B4GALT7, EDSP1, XGALT1, XGPT1, EDSSLA, beta-1,4-galactosyltransferase 7, EDSSPD1, XGPT. The table shows each extracted connection, where it came from and its confidence.
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4IRP, 4IRQ
1.00
infobox
B4GALT7
Band
5q35.3
1.00
infobox
B4GALT7
Band
13|13 B1
1.00
infobox
B4GALT7
Bgee
tendon of biceps brachii
1.00
infobox
B4GALT7
Bgee
right adrenal gland
1.00
infobox
B4GALT7
Bgee
left adrenal gland
1.00
infobox
B4GALT7
Bgee
left adrenal cortex
1.00
infobox
B4GALT7
Bgee
right adrenal cortex
1.00
infobox
B4GALT7
Bgee
anterior pituitary
1.00
infobox
B4GALT7
Bgee
apex of heart
1.00
infobox
B4GALT7
Bgee
body of pancreas
1.00
infobox
B4GALT7
Bgee
stromal cell of endometrium
1.00
infobox
B4GALT7
Bgee
body of stomach
1.00
infobox
B4GALT7
Bgee
saccule
1.00
infobox
B4GALT7
Bgee
otic vesicle
1.00
infobox
B4GALT7
Bgee
otic placode
1.00
infobox
B4GALT7
Bgee
cumulus cell
1.00
infobox
B4GALT7
Bgee
renal corpuscle
1.00
infobox
B4GALT7
Bgee
medullary collecting duct
1.00
infobox
B4GALT7
Bgee
decidua
1.00
infobox
B4GALT7
Bgee
granulocyte
1.00
infobox
B4GALT7
Bgee
blood
1.00
infobox
B4GALT7
Bgee
internal carotid artery
1.00
infobox
B4GALT7
BioGPS
More reference expression data
1.00
infobox
B4GALT7
Chr.
Chromosome 5 (human)
1.00
infobox
B4GALT7
Chr.
Chromosome 13 (mouse)
1.00
infobox
B4GALT7
Databases
NCBI: entry; OMA: entry
1.00
infobox
B4GALT7
End
177,610,330 bp
1.00
infobox
No triples extracted yet.
Related concept clusters Concept neighborhoods
Concept neighborhoods group terms that sit near one another in the extracted graph. They are useful for discovering adjacent language and context, but proximity does not by itself imply a factual relationship.
The concept neighborhoods around B4GALT7 bring nearby vocabulary together. In this analysis, examples include Activity, Gene and Mutations. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
B4GALT7
Activity
Gene
Mutations
Syndrome
Beta-1
Galactosyltransferase
Location
Enzyme
Human
Carbohydrate
Glycosaminoglycan
Search
b4galt7
Activity
Gene
Mutations
Syndrome
Beta-1
Galactosyltransferase
Location
Enzyme
Human
Carbohydrate
Glycosaminoglycan
Search
galactosyltransferase
Gene
Activity
Carbohydrate
End
Glycosaminoglycan
Golgi
Manganese
Membrane
Mouse
Protein
Search
Linkage
enzyme
Gene
Encoded
Activity
Galactosyltransferase
External
Available
Found
Pdb
Search
Structures
Linkage
Mutations
function
Golgi
Membrane
Protein
Search
Structures
Activity
Chromosome
Location
Bp
Chr
Human
Gene
gene
Location
Human
End
Mouse
Search
Band
Carbohydrate
Glycosaminoglycan
Golgi
Manganese
Membrane
Pdb
type ii membrane proteins
Golgi
Protein
Glycosaminoglycan
Mouse
Search
Membrane
Type
Linkage
Mutations
Syndrome
Activity
Function
carbohydrate
Glycosaminoglycan
End
Golgi
Manganese
Membrane
Mouse
Protein
Search
Chromosome
Function
Galactosyltransferase
Location
Connections between topic areas Semantic bridges
Semantic bridges connect parts of the graph that would otherwise be more separate. A bridge is a structural signal in this analysis, not a claim that the two topic areas are equivalent.
For B4GALT7, one of the stronger structural bridges in this analysis connects B4GALT7 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.
B4GALT7
Nodes28
Edges27
Triples100
Avg. degree1.93
Density0.071429
Components1
Source & methodology
TTTA analyzes the structure around B4GALT7 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
