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Avanafil: Art, Adverse effects & Overview

Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil is sold under the brand names Stendra and Spedra. It was invented at Mitsubishi Tanabe Pharma, formerly known as Tanabe Seiyaku Co., and licensed to Vivus Inc., which partnered with Menarini Group to commercialise Spedra in…

Language: English [EN]
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Avanafil topic overview

The analysis highlights Art, Adverse effects and Overview as prominent areas in the source structure around Avanafil.

Related topics
20
Source areas
4
Connected nodes
24
Extracted relationships
38
Concept neighborhoods
14
Bridge connections
24

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 12 topics
Adverse effects · 5 topics
Mechanism of action · 2 topics
Synthesis · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
G04BE10 (WHO)
CAS Number
330784-47-9 Y
ChEBI
CHEBI:66876
ChEMBL
ChEMBL1963681 N

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Adverse effects

Mechanism of action

Synthesis

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Avanafil connects Entity context

The extracted context around Avanafil shows recurring relationship patterns in the source. For example, Avanafil → Archived, Drug Information Portal, January, Medicine, National Library Another extracted example is Avanafil → AU: S4 (Prescription only), EU: Rx-only, UK: POM (Prescription only), US: ℞-only. Use these groups to spot repeated connection types before inspecting the individual relationships.

Avanafil

Top relations

related to External links · 5
Avanafil → Archived, Drug Information Portal, January, Medicine, National Library
Legal status · 4
Avanafil → AU: S4 (Prescription only), EU: Rx-only, UK: POM (Prescription only), US: ℞-only
License data · 3
Avanafil → EU EMA: by INN, US DailyMed: Avanafil, US FDA: Avanafil
has effect · 3
Avanafil → Although, The, While
related to Mechanism of action · 2
Avanafil → Avanafil's, The
3D model (JSmol) · 1
Avanafil → Interactive image
AHFS/Drugs.com · 1
Avanafil → Monograph
ATC code · 1
Avanafil → G04BE10 (WHO)
CAS Number · 1
Avanafil → 330784-47-9 Y
ChEBI · 1
Avanafil → CHEBI:66876

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

pde5 action fda spedra within minutes ema adverse effects inhibitor 27 names stendra co drugs erectile dysfunction penis sexual mechanism

Avanafil relationships Subject–Predicate–Object triples

TTTA extracted 38 structured relationships around Avanafil. Examples in this analysis include Avanafil → 3D model (JSmol) → Interactive image and Avanafil → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Avanafil3D model (JSmol)Interactive image1.00infobox
AvanafilAHFS/Drugs.comMonograph1.00infobox
AvanafilATC codeG04BE10 (WHO)1.00infobox
AvanafilCAS Number330784-47-9 Y1.00infobox
AvanafilChEBICHEBI:668761.00infobox
AvanafilChEMBLChEMBL1963681 N1.00infobox
AvanafilChemSpider8045620 Y1.00infobox
AvanafilCompTox Dashboard (EPA)DTXSID501867271.00infobox
AvanafilDrugBankDB06237 Y1.00infobox
AvanafilFormulaC23H26ClN7O31.00infobox
AvanafilIUPHAR/BPS74481.00infobox
AvanafilKEGGD03217 Y1.00infobox
AvanafilLegal statusAU: S4 (Prescription only)1.00infobox
AvanafilLegal statusUK: POM (Prescription only)1.00infobox
AvanafilLegal statusUS: ℞-only1.00infobox
AvanafilLegal statusEU: Rx-only1.00infobox
AvanafilLicense dataEU EMA: by INN1.00infobox
AvanafilLicense dataUS DailyMed: Avanafil1.00infobox
AvanafilLicense dataUS FDA: Avanafil1.00infobox
AvanafilMedlinePlusa6140101.00infobox
AvanafilMolar mass483.96 g·mol−11.00infobox
AvanafilPDB ligandE6L (PDBe, RCSB PDB)1.00infobox
AvanafilPubChem CID98699291.00infobox
AvanafilRoutes of administrationBy mouth1.00infobox
AvanafilTrade namesStendra1.00infobox
AvanafilUNIIDR5S136IVO1.00infobox
Avanafilis aPDE5 inhibitor approved for erectile dysfunction by the FDA on April 270.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Avanafil bring nearby vocabulary together. In this analysis, examples include Pde5, Dysfunction and Ema. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Avanafil
    • Pde5
    • Dysfunction
    • Ema
    • Erectile
    • Fda
    • Inhibitor
    • Names
    • Stendra
    • Action
    • Adverse
    • Effects
    • Approved
  • avanafil
    • Pde5
    • Dysfunction
    • Ema
    • Erectile
    • Fda
    • Inhibitor
    • Names
    • Stendra
    • Action
    • Adverse
    • Effects
    • Approved
  • erectile dysfunction
    • Dysfunction
    • Ema
    • Erectile
    • Fda
    • Inhibitor
    • Pde5
    • June
    • Co
    • Drugs
    • Mechanism
    • Names
    • Stendra
  • onset of action
    • Mechanism
    • Pde5
    • Co
    • Drugs
    • Dysfunction
    • Ema
    • Erectile
    • Fda
    • Inhibitor
    • Names
    • Sexual
    • Stendra
  • adverse effects
    • Effects
    • Co
    • Drugs
    • Dysfunction
    • Ema
    • Erectile
    • Fda
    • Inhibitor
    • Mechanism
    • Names
    • Occur
    • Stendra
  • mechanism of action
    • Mechanism
    • Pde5
    • Names
    • Sexual
    • Stendra
    • Co
    • Drugs
    • Dysfunction
    • Ema
    • Erectile
    • Fda
    • Inhibitor
  • pde5 inhibitor
    • Dysfunction
    • Ema
    • Erectile
    • Fda
    • Pde5
    • June
    • Co
    • Drugs
    • Mechanism
    • Names
    • Stendra
    • Action
  • fda
    • Ema
    • Inhibitor
    • Pde5
    • June
    • Co
    • Drugs
    • Mechanism
    • Names
    • Stendra
    • Action
    • Adverse
    • Effects

Connections between topic areas Semantic bridges

For Avanafil, one of the stronger structural bridges in this analysis connects Avanafil with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Avanafil — Overview · splits 12 ⟂ 13
Avanafil — Adverse effects · splits 19 ⟂ 6
Avanafil — Mechanism of action · splits 22 ⟂ 3

Map overview Semantic statistics

Avanafil

Nodes25
Edges24
Triples38
Avg. degree1.92
Density0.08
Components1

Source & methodology

TTTA analyzes the structure around Avanafil to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Adverse effects & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Avanafil · EN edition · Analysis: TopicsToTalkAbout

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