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Asialoglycoprotein receptor

The asialoglycoprotein receptors (ASGPR) are lectins which bind asialoglycoprotein and glycoproteins from which a sialic acid has been removed to expose galactose residues. The receptors, which are integral membrane proteins and are located on mammalian hepatocytes (liver cells), remove target glycoproteins from circulation. The asialoglycoprotein…

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Key facts & relationships

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Domains
InterPro
HGNC
742
Locus
Chr. 17 p13-p11
NCBI gene
432
OMIM
108360
RefSeq
NM_001671

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Overview

History

Mechanism of action

Advanced semantic analysis

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Map overview Semantic statistics

Asialoglycoprotein receptor

Nodes21
Edges20
Triples30
Avg. degree1.9
Density0.095238
Components1

How this topic connects Entity context

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Asialoglycoprotein receptor

Top relations

related to Mechanism of action · 9
Asialoglycoprotein receptor → Ca2, CRD, Each, H1, H2, In, N-terminus, The, The CRD
related to history · 5
Asialoglycoprotein receptor → Morell, The, This, Thus, Upon
related to Function · 3
Asialoglycoprotein receptor → Asialoglycoprotein, More, N-acetylgalactosaminyl-containing
Domains · 1
Asialoglycoprotein receptor → InterPro
HGNC · 1
Asialoglycoprotein receptor → 742
Locus · 1
Asialoglycoprotein receptor → Chr. 17 p13-p11
NCBI gene · 1
Asialoglycoprotein receptor → 432
OMIM · 1
Asialoglycoprotein receptor → 108360
RefSeq · 1
Asialoglycoprotein receptor → NM_001671
Search for · 1
Asialoglycoprotein receptor → Search forStructuresSwiss-modelDomainsInterPro

Important terminology Word statistics

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Important terminology

asialoglycoprotein receptor receptors galactose acid sialic liver cells glycoproteins affinity asgpr terminal sugars asgp hepatocytes interaction removed subunits asgr subunit

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Asialoglycoprotein receptorDomainsInterPro1.00infobox
Asialoglycoprotein receptorHGNC7421.00infobox
Asialoglycoprotein receptorLocusChr. 17 p13-p111.00infobox
Asialoglycoprotein receptorNCBI gene4321.00infobox
Asialoglycoprotein receptorOMIM1083601.00infobox
Asialoglycoprotein receptorRefSeqNM_0016711.00infobox
Asialoglycoprotein receptorSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Asialoglycoprotein receptorStructuresSwiss-model1.00infobox
Asialoglycoprotein receptorSymbolASGR11.00infobox
Asialoglycoprotein receptorUniProtP073061.00infobox
dimersinstance ofThese subunits may form different quaternary forms0.80text
trimersinstance ofThese subunits may form different quaternary forms0.80text

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