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Rho GTPase-activating protein 4 is an enzyme that in humans is encoded by the ARHGAP4 gene. It has been shown to regulate cell motility and axonal outgrowth in vitro.
The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around ARHGAP4.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around ARHGAP4 shows recurring relationship patterns in the source. For example, ARHGAP4 → cytoplasm, cytoskeleton organization, cytosol, Golgi apparatus, growth cone, GTPase activator activity, identical protein binding, microtubule, negative regulation of axon extension, negative regulation of cell migration, negative regulation of fibroblast migration, nervous system development, positive regulation of GTPase activity, positive regulation of signal transduction, protein binding, regulation of small GTPase mediated signal transduction, Rho protein signal transduction, signal transduction Another extracted example is ARHGAP4 → apex of heart, appendix, blood, bone marrow, embryo, granulocyte, lymph node, mesenteric lymph nodes, monocyte, otic vesicle, right hemisphere of cerebellum, right lung, spleen, subcutaneous adipose tissue, thymus, tibiofemoral joint, upper lobe of left lung. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp human gene chr band chromosome location rho protein uniprot mouse cell external gtpase search 934 999 end 153 a7
TTTA extracted 77 structured relationships around ARHGAP4. Examples in this analysis include ARHGAP4 → Aliases → ARHGAP4, C1, RGC1, RhoGAP4, SrGAP4, p115, Rho GTPase activating protein 4 and ARHGAP4 → Available structures → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2EPD. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| ARHGAP4 | Aliases | ARHGAP4, C1, RGC1, RhoGAP4, SrGAP4, p115, Rho GTPase activating protein 4 | 1.00 | infobox |
| ARHGAP4 | Available structures | Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2EPD | 1.00 | infobox |
| ARHGAP4 | Band | Xq28 | 1.00 | infobox |
| ARHGAP4 | Band | X|X A7.3 | 1.00 | infobox |
| ARHGAP4 | Bgee | granulocyte | 1.00 | infobox |
| ARHGAP4 | Bgee | spleen | 1.00 | infobox |
| ARHGAP4 | Bgee | monocyte | 1.00 | infobox |
| ARHGAP4 | Bgee | lymph node | 1.00 | infobox |
| ARHGAP4 | Bgee | blood | 1.00 | infobox |
| ARHGAP4 | Bgee | right lung | 1.00 | infobox |
| ARHGAP4 | Bgee | upper lobe of left lung | 1.00 | infobox |
| ARHGAP4 | Bgee | appendix | 1.00 | infobox |
| ARHGAP4 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| ARHGAP4 | Bgee | apex of heart | 1.00 | infobox |
| ARHGAP4 | Bgee | thymus | 1.00 | infobox |
| ARHGAP4 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| ARHGAP4 | Bgee | tibiofemoral joint | 1.00 | infobox |
| ARHGAP4 | Bgee | bone marrow | 1.00 | infobox |
| ARHGAP4 | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| ARHGAP4 | Bgee | otic vesicle | 1.00 | infobox |
| ARHGAP4 | Bgee | embryo | 1.00 | infobox |
| ARHGAP4 | BioGPS | More reference expression data | 1.00 | infobox |
| ARHGAP4 | Chr. | X chromosome (human) | 1.00 | infobox |
| ARHGAP4 | Chr. | X chromosome (mouse) | 1.00 | infobox |
| ARHGAP4 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| ARHGAP4 | End | 153,934,999 bp | 1.00 | infobox |
| ARHGAP4 | End | 72,965,476 bp | 1.00 | infobox |
| ARHGAP4 | Ensembl | ENSG00000089820 | 1.00 | infobox |
| ARHGAP4 | Entrez | 393 | 1.00 | infobox |
| ARHGAP4 | External IDs | OMIM: 300023; MGI: 2159577; GeneCards: ARHGAP4 | 1.00 | infobox |
The concept neighborhoods around ARHGAP4 bring nearby vocabulary together. In this analysis, examples include Protein, Rho and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
Bridges highlight paths between different parts of the ARHGAP4 map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around ARHGAP4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — ARHGAP4 · EN edition · Analysis: TopicsToTalkAbout