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Darbepoetin alfa

Darbepoetin alfa (INN) /dɑːrbəˈpoʊɪtɪn/ is a re-engineered form of erythropoietin containing 5 amino acid changes (N30, T32, V87, N88, T90) resulting in the creation of 2 new sites for N-linked carbohydrate addition. It has a 3-fold longer serum half-life compared to epoetin alpha and epoetin beta. It stimulates erythropoiesis (increases red blood cell…

Community & Culture

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Topic orientation

Darbepoetin alfa at a glance

The strongest research directions include Adverse effects and Society and culture. Use the connected concepts below as starting points, not as a keyword checklist.

Research this topic

Explore the main themes, entities and connections around Darbepoetin alfa. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

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Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AHFS/Drugs.com
Monograph
ATC code
B03XA02 (WHO)
CAS Number
209810-58-2 N
ChemSpider
none
CompTox Dashboard (EPA)
DTXSID7039678
DrugBank
DB00012 Y

Topics to explore

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Overview

Adverse effects

Mechanism of action

Safety advisories in anemic cancer patients

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How this topic connects Entity context

Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.

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Darbepoetin alfa

Top relations

related to Society and culture · 8
Darbepoetin alfa → Its, Johann Mühlegg, Larisa Lazutina, Like EPO, Olga Danilova, Russia, Spain, Winter Olympic Games
has effect · 6
Darbepoetin alfa → Darbepoetin, In, Other, RBC, To, United States
Legal status · 4
Darbepoetin alfa → AU: S4 (Prescription only), EU: Rx-only, In general: ℞ (Prescription only), US: ℞-only
related to Pregnancy and lactation · 3
Darbepoetin alfa → Darbepoetin, It, United States
related to Mechanism of action · 2
Darbepoetin alfa → Darbepoetin, RBC
AHFS/Drugs.com · 1
Darbepoetin alfa → Monograph
ATC code · 1
Darbepoetin alfa → B03XA02 (WHO)
CAS Number · 1
Darbepoetin alfa → 209810-58-2 N
ChemSpider · 1
Darbepoetin alfa → none
CompTox Dashboard (EPA) · 1
Darbepoetin alfa → DTXSID7039678

Important terminology Word statistics

Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

darbepoetin alfa patients cancer anemia use chemotherapy failure aranesp erythropoietin epo chronic kidney treatment administration amgen pregnancy clinical red cell

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
Darbepoetin alfaAHFS/Drugs.comMonograph1.00infobox
Darbepoetin alfaATC codeB03XA02 (WHO)1.00infobox
Darbepoetin alfaCAS Number209810-58-2 N1.00infobox
Darbepoetin alfaChemSpidernone1.00infobox
Darbepoetin alfaCompTox Dashboard (EPA)DTXSID70396781.00infobox
Darbepoetin alfaDrugBankDB00012 Y1.00infobox
Darbepoetin alfaFormulaC815H1317N233O241S51.00infobox
Darbepoetin alfaLegal statusAU: S4 (Prescription only)1.00infobox
Darbepoetin alfaLegal statusUS: ℞-only1.00infobox
Darbepoetin alfaLegal statusEU: Rx-only1.00infobox
Darbepoetin alfaLegal statusIn general: ℞ (Prescription only)1.00infobox
Darbepoetin alfaLicense dataUS DailyMed: Darbepoetin alfa1.00infobox
Darbepoetin alfaMedlinePlusa6040221.00infobox
Darbepoetin alfaMolar mass18396.19 g·mol−11.00infobox
Darbepoetin alfaPregnancy categoryAU: B31.00infobox
Darbepoetin alfaRoutes of administrationIntravenous, subcutaneous1.00infobox
Darbepoetin alfaTrade namesAranesp1.00infobox
Darbepoetin alfaUNII15UQ94PT4P1.00infobox

Related concept clusters Concept neighborhoods

Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Map overview Semantic statistics

    Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

    Darbepoetin alfa

    Nodes49
    Edges48
    Triples39
    Avg. degree1.96
    Density0.040816
    Components1
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