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Afoxolaner

Afoxolaner is an insecticide and acaricide that belongs to the isoxazoline chemical compound group. It is used to kill fleas and ticks in small animals.

Standards, Brand names & Mechanism

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Explore the main themes, entities and connections around Afoxolaner. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Brand names

6 related topics

Mechanism

4 related topics

Legal status

1 related topics

Overview

3 related topics

Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATCvet code
QP53BE01 (WHO)
Bioavailability
74% (Tmax = 2–4 hours)
CAS Number
1093861-60-9
ChEMBL
ChEMBL2219412

Topics to explore

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Overview

Mechanism

Legal status

Brand names

Advanced semantic analysis

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Map overview Semantic statistics

Afoxolaner

Nodes19
Edges18
Triples38
Avg. degree1.89
Density0.105263
Components1

How this topic connects Entity context

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Afoxolaner

Top relations

related to Mechanism · 5
Afoxolaner → GABA, GABA-gated, GABA-receptors, Selectivity, The
Legal status · 4
Afoxolaner → CA: ℞-only, EU: Rx-only, OTC (RU), US: ℞-only
related to Brand names · 4
Afoxolaner → Frontpro, Nexgard, Nexgard Spectra, They
3D model (JSmol) · 1
Afoxolaner → Interactive image
AHFS/Drugs.com · 1
Afoxolaner → International Drug Names
ATCvet code · 1
Afoxolaner → QP53BE01 (WHO)
Bioavailability · 1
Afoxolaner → 74% (Tmax = 2–4 hours)
CAS Number · 1
Afoxolaner → 1093861-60-9
ChEMBL · 1
Afoxolaner → ChEMBL2219412
ChemSpider · 1
Afoxolaner → 28651525

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nexgard legal status names fleas ticks tick flea frontpro drug number insecticide acaricide isoxazoline gaba chloride insect insects selectivity given

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Afoxolaner3D model (JSmol)Interactive image1.00infobox
AfoxolanerAHFS/Drugs.comInternational Drug Names1.00infobox
AfoxolanerATCvet codeQP53BE01 (WHO)1.00infobox
AfoxolanerBioavailability74% (Tmax = 2–4 hours)1.00infobox
AfoxolanerCAS Number1093861-60-91.00infobox
AfoxolanerChEMBLChEMBL22194121.00infobox
AfoxolanerChemSpider286515251.00infobox
AfoxolanerChiralityRacemic mixture1.00infobox
AfoxolanerCompTox Dashboard (EPA)DTXSID501489211.00infobox
AfoxolanerDrugBankDB113691.00infobox
AfoxolanerECHA InfoCard100.267.8221.00infobox
AfoxolanerElimination half-life14 days1.00infobox
AfoxolanerExcretionBile duct (major route)1.00infobox
AfoxolanerFormulaC26H17ClF9N3O31.00infobox
AfoxolanerKEGGD103611.00infobox
AfoxolanerLegal statusCA: ℞-only1.00infobox
AfoxolanerLegal statusUS: ℞-only1.00infobox
AfoxolanerLegal statusEU: Rx-only1.00infobox
AfoxolanerLegal statusOTC (RU)1.00infobox
AfoxolanerLicense dataUS DailyMed: Afoxolaner1.00infobox
AfoxolanerMolar mass625.88 g·mol−11.00infobox
AfoxolanerOther names4-[(5RS)-5-(5-Chloro-α,α,α-trifluoro-m-tolyl)-4,5-dihydro-5-(trifluoromethyl)-1,2-oxazol-3-yl]-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]naphthalene-1-carboxamide1.00infobox
AfoxolanerPronunciation/eɪˌfɒksoʊˈlænər/ ay-FOK-soh-LAN-ər1.00infobox
AfoxolanerPubChem CID251542491.00infobox
AfoxolanerRoutes of administrationBy mouth1.00infobox
AfoxolanerTrade namesNexgard, Frontpro1.00infobox
AfoxolanerUNII02L07H6D0U1.00infobox
Afoxolaneris ainsecticide and acaricide that belongs to the isoxazoline chemical compound group0.90text

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