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Afoxolaner: Standards, Brand names & Mechanism

Afoxolaner is an insecticide and acaricide that belongs to the isoxazoline chemical compound group. It is used to kill fleas and ticks in small animals.

Language: English [EN]
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Afoxolaner topic overview

The analysis highlights Standards, Brand names and Mechanism as prominent areas in the source structure around Afoxolaner.

Related topics
14
Source areas
4
Connected nodes
18
Extracted relationships
36
Related term clusters
11
Bridge connections
18

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Brand names · 6 topics
Mechanism · 4 topics
Overview · 3 topics
Legal status · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATCvet code
QP53BE01 (WHO)
Bioavailability
74% (Tmax = 2–4 hours)
CAS Number
1093861-60-9
ChEMBL
ChEMBL2219412

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Afoxolaner
3Insecticide · Acaricide · Isoxazoline
6Active ingredient · Milbemycin oxime · Flea
5GABA receptor · Paralysis · Mammal

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Mechanism

Legal status

Brand names

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Afoxolaner connects Entity context

The extracted context around Afoxolaner shows recurring relationship patterns in the source. For example, Afoxolaner → CA: ℞-only, EU: Rx-only, OTC (RU), US: ℞-only Another extracted example is Afoxolaner → GABA, GABA-gated, GABA-receptors, Selectivity. Use these groups to spot repeated connection types before inspecting the individual relationships.

Afoxolaner

Top relations

Legal status · 4
Afoxolaner → CA: ℞-only, EU: Rx-only, OTC (RU), US: ℞-only
related to Mechanism · 4
Afoxolaner → GABA, GABA-gated, GABA-receptors, Selectivity
related to Brand names · 3
Afoxolaner → Frontpro, Nexgard, Nexgard Spectra
3D model (JSmol) · 1
Afoxolaner → Interactive image
AHFS/Drugs.com · 1
Afoxolaner → International Drug Names
ATCvet code · 1
Afoxolaner → QP53BE01 (WHO)
Bioavailability · 1
Afoxolaner → 74% (Tmax = 2–4 hours)
CAS Number · 1
Afoxolaner → 1093861-60-9
ChEMBL · 1
Afoxolaner → ChEMBL2219412
ChemSpider · 1
Afoxolaner → 28651525

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nexgard legal status names fleas ticks tick flea frontpro drug number insecticide acaricide isoxazoline gaba chloride insect insects selectivity given

Afoxolaner relationships Subject–Predicate–Object triples

TTTA extracted 36 structured relationships around Afoxolaner. Examples in this analysis include Afoxolaner → 3D model (JSmol) → Interactive image and Afoxolaner → AHFS/Drugs.com → International Drug Names. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Afoxolaner3D model (JSmol)Interactive image1.00infobox
AfoxolanerAHFS/Drugs.comInternational Drug Names1.00infobox
AfoxolanerATCvet codeQP53BE01 (WHO)1.00infobox
AfoxolanerBioavailability74% (Tmax = 2–4 hours)1.00infobox
AfoxolanerCAS Number1093861-60-91.00infobox
AfoxolanerChEMBLChEMBL22194121.00infobox
AfoxolanerChemSpider286515251.00infobox
AfoxolanerChiralityRacemic mixture1.00infobox
AfoxolanerCompTox Dashboard (EPA)DTXSID501489211.00infobox
AfoxolanerDrugBankDB113691.00infobox
AfoxolanerECHA InfoCard100.267.8221.00infobox
AfoxolanerElimination half-life14 days1.00infobox
AfoxolanerExcretionBile duct (major route)1.00infobox
AfoxolanerFormulaC26H17ClF9N3O31.00infobox
AfoxolanerKEGGD103611.00infobox
AfoxolanerLegal statusCA: ℞-only1.00infobox
AfoxolanerLegal statusUS: ℞-only1.00infobox
AfoxolanerLegal statusEU: Rx-only1.00infobox
AfoxolanerLegal statusOTC (RU)1.00infobox
AfoxolanerLicense dataUS DailyMed: Afoxolaner1.00infobox
AfoxolanerMolar mass625.88 g·mol−11.00infobox
AfoxolanerOther names4-[(5RS)-5-(5-Chloro-α,α,α-trifluoro-m-tolyl)-4,5-dihydro-5-(trifluoromethyl)-1,2-oxazol-3-yl]-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]naphthalene-1-carboxamide1.00infobox
AfoxolanerPronunciation/eɪˌfɒksoʊˈlænər/ ay-FOK-soh-LAN-ər1.00infobox
AfoxolanerPubChem CID251542491.00infobox
AfoxolanerRoutes of administrationBy mouth1.00infobox
AfoxolanerTrade namesNexgard, Frontpro1.00infobox
AfoxolanerUNII02L07H6D0U1.00infobox
Afoxolaneris ainsecticide and acaricide that belongs to the isoxazoline chemical compound group0.90text

Related concept clusters Related term clusters

The concept neighborhoods around Afoxolaner bring nearby vocabulary together. In this analysis, examples include Frontpro, Gaba and Given. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Afoxolaner
    • Frontpro
    • Gaba
    • Given
    • Nexgard
    • Acaricide
    • Belongs
    • Brand
    • Chemical
    • Compound
    • Group
    • Insecticide
    • Isoxazoline
  • afoxolaner
    • Frontpro
    • Gaba
    • Given
    • Nexgard
    • Acaricide
    • Belongs
    • Brand
    • Chemical
    • Compound
    • Group
    • Insecticide
    • Isoxazoline
  • mechanism
    • Brand
    • Legal
    • Names
    • References
    • Status
    • Use
    • Chloride
    • Drug
    • Frontpro
    • Gaba
    • Insect
    • Number
  • legal status
    • Brand
    • Mechanism
    • Names
    • References
    • Status
    • Use
    • Chloride
    • Drug
    • Frontpro
    • Gaba
    • Insect
    • Number
  • brand names
    • Legal
    • Mechanism
    • Names
    • References
    • Status
    • Use
    • Chloride
    • Drug
    • Frontpro
    • Gaba
    • Insect
    • Number
  • gaba receptor
    • Legal
    • Mechanism
    • Names
    • References
    • Status
    • Use
    • Chloride
    • Insect
    • Insects
    • Number
    • Nexgard
  • acaricide
    • Belongs
    • Chemical
    • Compound
    • Group
    • Insecticide
    • Isoxazoline
    • Afoxolaner
  • isoxazoline
    • Acaricide
    • Belongs
    • Chemical
    • Compound
    • Group
    • Insecticide
    • Afoxolaner

Connections between topic areas Semantic bridges

For Afoxolaner, one of the stronger structural bridges in this analysis connects Afoxolaner with Brand names. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Afoxolaner — Brand names · splits 12 ⟂ 7
Afoxolaner — Mechanism · splits 14 ⟂ 5
Afoxolaner — Overview · splits 15 ⟂ 4

Map overview Semantic statistics

Afoxolaner

Nodes19
Edges18
Triples36
Avg. degree1.89
Density0.105263
Components1

Source & methodology

TTTA analyzes the structure around Afoxolaner to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Brand names & Mechanism, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Afoxolaner · EN edition · Analysis: TopicsToTalkAbout

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