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Acrosin

Acrosin is a digestive enzyme that acts as a protease. In humans, acrosin is encoded by the ACR gene. Acrosin is released from the acrosome of spermatozoa as a consequence of the acrosome reaction. It aids in the penetration of the Zona Pellucida.

Structure, Biological Function & Disease and Pharmaceutical Relevance

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Structure

6 related topics

Biological Function

4 related topics

Disease and Pharmaceutical Relevance

4 related topics

Enzyme Mechanism

1 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

BRENDA
enzyme data
CAS no.
9068-57-9
EC no.
3.4.21.10
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO
KEGG
enzyme entry

Topics to explore

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Overview

Enzyme Mechanism

Biological Function

Structure

Disease and Pharmaceutical Relevance

Advanced semantic analysis

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Map overview Semantic statistics

Acrosin

Nodes28
Edges27
Triples70
Avg. degree1.93
Density0.071429
Components1

How this topic connects Entity context

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Acrosin

Top relations

related to Structure · 22
Acrosin → Arg, Arg-22, Asn-169, Asn-2, Asp-102, C-terminal, Following, His-57, Lys, N-glycosylation, N-terminal, Proacrosin, S1, Ser-195, The, The S1, There, These, This, Trp-215
related to Disease and Pharmaceutical Relevance · 8
Acrosin → Although, HIV, In, Moreover, Other, This, Thus, While
related to Enzyme Mechanism · 8
Acrosin → Collapse, Deprotonated Ser-195, Finally, First, H2N-R1, His-57, Ser-195, The
related to External links · 8
Acrosin → Medicine, Medicine Medical Subject Headings, MeSH, National Library, S01, The MEROPS, This, United States National Library
related to Biological Function · 7
Acrosin → After, It, The, This, Thus, Under, Upon
is a · 2
Acrosin → digestive enzyme that acts as a protease, highly charged patch
BRENDA · 1
Acrosin → enzyme data
CAS no. · 1
Acrosin → 9068-57-9
EC no. · 1
Acrosin → 3.4.21.10
ExPASy · 1
Acrosin → NiceZyme view

Important terminology Word statistics

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Important terminology

pellucida zona spermatozoa acrosome binding enzyme protease β-acrosin reaction serine his-57 thus found penetration ser-195 serve residues active role protein

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
AcrosinBRENDAenzyme data1.00infobox
AcrosinCAS no.9068-57-91.00infobox
AcrosinEC no.3.4.21.101.00infobox
AcrosinExPASyNiceZyme view1.00infobox
AcrosinGene OntologyAmiGO / QuickGO1.00infobox
AcrosinKEGGenzyme entry1.00infobox
AcrosinMetaCycmetabolic pathway1.00infobox
AcrosinNCBIproteins1.00infobox
AcrosinPDB structuresRCSB PDB PDBe PDBsum1.00infobox
AcrosinPMCarticles1.00infobox
AcrosinPubMedarticles1.00infobox
AcrosinRheareactions1.00infobox
AcrosinSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox
Acrosinis adigestive enzyme that acts as a protease0.90text
Acrosinis ahighly charged patch0.90text

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    Min side: 3
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