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Acarbose

Acarbose (INN) is an anti-diabetic drug used to treat diabetes mellitus type 2 and (in some countries), prediabetes. It is sold in Europe and China as Glucobay (Bayer AG), in North America as Precose (Bayer Pharmaceuticals), and in Canada as Prandase (Bayer AG).

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A10BF01 (WHO)
Bioavailability
Extremely low
CAS Number
56180-94-0 Y
ChEMBL
ChEMBL1566 Y

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Overview

Medical uses

Adverse effects

Pharmacology

Natural distribution

In molecular biology

Research

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Map overview Semantic statistics

Acarbose

Nodes67
Edges66
Triples73
Avg. degree1.97
Density0.029851
Components1

How this topic connects Entity context

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Acarbose

Top relations

related to Metabolism · 10
Acarbose → Analog, CDase, Human, IM6501, It, Lactobacillus, Streptococcus, The, Thermus, ThMA
related to Efficacy · 9
Acarbose → A1c, Among, Cochrane, HbA1c, II, In, Individuals, It, Its
has effect · 8
Acarbose → Even, GI, In, It, Liver, One, Since, Sucrose
related to Mechanism of action · 7
Acarbose → HbA1c, However, In, Inhibition, It, Less, Pancreatic
related to Research · 3
Acarbose → In, Most, T2DM
Legal status · 2
Acarbose → UK: POM (Prescription only), US: ℞-only
related to Combination therapy · 2
Acarbose → HbA1c, The
related to Natural distribution · 2
Acarbose → Actinoplanes, In
3D model (JSmol) · 1
Acarbose → Interactive image
AHFS/Drugs.com · 1
Acarbose → Monograph

Important terminology Word statistics

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Important terminology

glucose patients carbohydrates hba1c alpha-amylase diabetes effects glucosidase levels gut type diabetic alpha-glucosidase studies effect enzymes human bacteria use one

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Acarbose3D model (JSmol)Interactive image1.00infobox
AcarboseAHFS/Drugs.comMonograph1.00infobox
AcarboseATC codeA10BF01 (WHO)1.00infobox
AcarboseBioavailabilityExtremely low1.00infobox
AcarboseCAS Number56180-94-0 Y1.00infobox
AcarboseChEMBLChEMBL1566 Y1.00infobox
AcarboseChemSpider392239 Y1.00infobox
AcarboseCompTox Dashboard (EPA)DTXSID80460341.00infobox
AcarboseDrugBankDB00284 Y1.00infobox
AcarboseECHA InfoCard100.054.5551.00infobox
AcarboseElimination half-life2 hours1.00infobox
AcarboseExcretionKidney (less than 2%)1.00infobox
AcarboseFormulaC25H43NO181.00infobox
AcarboseIUPHAR/BPS67911.00infobox
AcarboseKEGGD00216 Y1.00infobox
AcarboseLegal statusUK: POM (Prescription only)1.00infobox
AcarboseLegal statusUS: ℞-only1.00infobox
AcarboseLicense dataUS DailyMed: Acarbose1.00infobox
AcarboseMedlinePlusa6960151.00infobox
AcarboseMetabolismGastrointestinal tract1.00infobox
AcarboseMolar mass645.608 g·mol−11.00infobox
AcarboseOther names(2R,3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5- {[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl- 5-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3- (hydroxymethyl)cyclohex-2-en-1-yl]amino} tetrahydro-2H-…1.00infobox
AcarbosePregnancy categoryAU: B31.00infobox
AcarbosePubChem CID4442541.00infobox
AcarboseRoutes of administrationBy mouth1.00infobox
AcarboseTrade namesGlucobay, Precose, Prandase1.00infobox
AcarboseUNIIT58MSI464G1.00infobox
Acarboseis astarch blocker that works by inhibiting alpha glucosidase0.90text

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