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Acanthosis nigricans is a cutaneous finding characterized by brown-to-black, velvety hyperpigmentation of the skin, most often affecting body folds such as the posterior neck, axillae, groin and umbilicus. It is strongly associated with insulin resistance and hyperinsulinaemia, including in type 2 diabetes and metabolic syndrome. Excess insulin activates…
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nigricans acanthosis may insulin metabolic associated resistance syndrome obesity skin type include reported diabetes studies also therapies malignancy hyperpigmentation common
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Acanthosis nigricans | Specialty | Dermatology | 1.00 | infobox |
| Acanthosis nigricans | is a | cutaneous finding characterized by brown-to-black | 0.90 | text |
| Acanthosis nigricans | is a | autosomal dominant condition presenting at birth or during childhood.Familial acanthosis nigricansEndocrine | 0.90 | text |
| Acanthosis nigricans | is a | visible marker of insulin resistance | 0.90 | text |
| Acanthosis nigricans | is a | autosomal dominant condition presenting at birth or during childhood.Familial acanthosis nigricans Endocrine | 0.90 | text |
| the posterior neck | instance of | most often affecting body folds | 0.80 | text |
| axillae | instance of | most often affecting body folds | 0.80 | text |
| groin | instance of | most often affecting body folds | 0.80 | text |
| umbilicus | instance of | most often affecting body folds | 0.80 | text |
| hypothyroidism | instance of | obesity and endocrine disorders | 0.80 | text |
| acromegaly | instance of | obesity and endocrine disorders | 0.80 | text |
| polyendocrine metabolic ovarian syndrome | instance of | obesity and endocrine disorders | 0.80 | text |
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