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Acanthosis nigricans

Acanthosis nigricans is a cutaneous finding characterized by brown-to-black, velvety hyperpigmentation of the skin, most often affecting body folds such as the posterior neck, axillae, groin and umbilicus. It is strongly associated with insulin resistance and hyperinsulinaemia, including in type 2 diabetes and metabolic syndrome. Excess insulin activates…

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Specialty
Dermatology

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Acanthosis nigricans

Nodes23
Edges22
Triples64
Avg. degree1.91
Density0.086957
Components1

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Acanthosis nigricans

Top relations

related to Epidemiology · 7
Acanthosis nigricans → Acanthosis, African, Asian, Higher, Hispanic/Latino, In, Native American
related to Obesity and pseudoacanthosis nigricans (Type III) · 6
Acanthosis nigricans → Elevated, HAIR-AN, In, Insulin, Most, This
has treatment · 5
Acanthosis nigricans → AN, Drug-induced AN, Management, Reported, When AN
related to Malignancy (Type V) · 5
Acanthosis nigricans → Additional, It, Less, Malignant, Mucosal
related to Prognosis · 5
Acanthosis nigricans → Drug-induced, Hereditary, Malignancy-associated, Obesity, The
is a · 4
Acanthosis nigricans → autosomal dominant condition presenting at birth or during childhood.Familial acanthosis nigricans Endocrine, autosomal dominant condition presenting at birth or during childhood.Familial acanthosis nigricansEndocrine, cutaneous finding characterized by brown-to-black, visible marker of insulin resistance
has cause · 4
Acanthosis nigricans → Acanthosis, Cushing's, It, Review
related to Pathophysiology · 4
Acanthosis nigricans → Acanthosis, Contributing, Hyperinsulinaemia, IGF-1
related to Diagnosis · 3
Acanthosis nigricans → Acanthosis, Evaluation, Investigations
related to Pediatric associations · 3
Acanthosis nigricans → Cross-sectional, In, Longitudinal

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Important terminology

nigricans acanthosis may insulin metabolic associated resistance syndrome obesity skin type include reported diabetes studies also therapies malignancy hyperpigmentation common

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Acanthosis nigricansSpecialtyDermatology1.00infobox
Acanthosis nigricansis acutaneous finding characterized by brown-to-black0.90text
Acanthosis nigricansis aautosomal dominant condition presenting at birth or during childhood.Familial acanthosis nigricansEndocrine0.90text
Acanthosis nigricansis avisible marker of insulin resistance0.90text
Acanthosis nigricansis aautosomal dominant condition presenting at birth or during childhood.Familial acanthosis nigricans Endocrine0.90text
the posterior neckinstance ofmost often affecting body folds0.80text
axillaeinstance ofmost often affecting body folds0.80text
groininstance ofmost often affecting body folds0.80text
umbilicusinstance ofmost often affecting body folds0.80text
hypothyroidisminstance ofobesity and endocrine disorders0.80text
acromegalyinstance ofobesity and endocrine disorders0.80text
polyendocrine metabolic ovarian syndromeinstance ofobesity and endocrine disorders0.80text

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