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ABCE1: Overview, Structure & Function

ATP-binding cassette sub-family E member 1 (ABCE1) also known as RNase L inhibitor (RLI) is an enzyme that in humans is encoded by the ABCE1 gene.

Language: English [EN]
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ABCE1 topic overview

The analysis highlights Overview, Structure and Function as prominent areas in the source structure around ABCE1.

Related topics
24
Source areas
3
Connected nodes
27
Extracted relationships
86
Concept neighborhoods
15
Bridge connections
27

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 15 topics
Structure · 5 topics
Function · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ABCE1, ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I, ATP binding cassette subfamily E member 1, RLI1
Band
4q31.21 · 8|8 C1
Bgee
gonad · islet of Langerhans · ventricular zone · Achilles tendon · stromal cell of endometrium
BioGPS
n/a
Chr.
Chromosome 4 (human) · Chromosome 8 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ABCE1 connects Entity context

The extracted context around ABCE1 shows recurring relationship patterns in the source. For example, ABCE1 → ATP binding, ATPase activity, cytoplasm, cytosol, defense response to virus, endoribonuclease inhibitor activity, eukaryotic translation initiation factor 3 complex, iron ion binding, membrane, mitochondrial matrix, mitochondrion, negative regulation of endoribonuclease activity, nucleotide binding, protein binding, regulation of type I interferon-mediated signaling pathway, ribosomal small subunit binding, ribosomal subunit export from nucleus, translational initiation, translational termination, viral process Another extracted example is ABCE1 → abdominal wall, Achilles tendon, body of pancreas, cumulus cell, dermis, epiblast, ganglionic eminence, gonad, Gonadal ridge, islet of Langerhans, lacrimal gland, mandibular prominence, maxillary prominence, primitive streak, rectum, secondary oocyte, stromal cell of endometrium, testicle, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

ABCE1

Top relations

Gene ontology · 20
ABCE1 → ATP binding, ATPase activity, cytoplasm, cytosol, defense response to virus, endoribonuclease inhibitor activity, eukaryotic translation initiation factor 3 complex, iron ion binding, membrane, mitochondrial matrix, mitochondrion, negative regulation of endoribonuclease activity, nucleotide binding, protein binding, regulation of type I interferon-mediated signaling pathway, ribosomal small subunit binding, ribosomal subunit export from nucleus, translational initiation, translational termination, viral process
Bgee · 19
ABCE1 → abdominal wall, Achilles tendon, body of pancreas, cumulus cell, dermis, epiblast, ganglionic eminence, gonad, Gonadal ridge, islet of Langerhans, lacrimal gland, mandibular prominence, maxillary prominence, primitive streak, rectum, secondary oocyte, stromal cell of endometrium, testicle, ventricular zone
RNA expression pattern · 19
ABCE1 → abdominal wall, Achilles tendon, body of pancreas, cumulus cell, dermis, epiblast, ganglionic eminence, gonad, Gonadal ridge, islet of Langerhans, lacrimal gland, mandibular prominence, maxillary prominence, primitive streak, rectum, secondary oocyte, stromal cell of endometrium, testicle, ventricular zone
related to Ribosome recycling · 4
ABCE1 → In, Pelota, Recycling, The
Band · 2
ABCE1 → 4q31.21, 8|8 C1
Chr. · 2
ABCE1 → Chromosome 4 (human), Chromosome 8 (mouse)
End · 2
ABCE1 → 145,129,524 bp, 80,438,369 bp
is a · 2
ABCE1 → ATPase that is a member of the ATP-binding cassette, essential and highly conserved protein that is required for both eukaryotic translation initiation as well as ribosome biogenesis
related to External links · 2
ABCE1 → GeneCardsP61221 UniProt, NCBI AceView
Aliases · 1
ABCE1 → ABCE1, ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I, ATP binding cassette subfamily E member 1, RLI1

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

rli protein initiation ribosome human rnase abc atp bp function cell chr band inhibitor translation also gene biogenesis cassette known

ABCE1 relationships Subject–Predicate–Object triples

TTTA extracted 86 structured relationships around ABCE1. Examples in this analysis include ABCE1 → Aliases → ABCE1, ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I, ATP binding cassette subfamily E member 1, RLI1 and ABCE1 → Band → 4q31.21. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ABCE1AliasesABCE1, ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I, ATP binding cassette subfamily E member 1, RLI11.00infobox
ABCE1Band4q31.211.00infobox
ABCE1Band8|8 C11.00infobox
ABCE1Bgeegonad1.00infobox
ABCE1Bgeeislet of Langerhans1.00infobox
ABCE1Bgeeventricular zone1.00infobox
ABCE1BgeeAchilles tendon1.00infobox
ABCE1Bgeestromal cell of endometrium1.00infobox
ABCE1Bgeetesticle1.00infobox
ABCE1Bgeeganglionic eminence1.00infobox
ABCE1Bgeesecondary oocyte1.00infobox
ABCE1Bgeebody of pancreas1.00infobox
ABCE1Bgeerectum1.00infobox
ABCE1Bgeeepiblast1.00infobox
ABCE1Bgeecumulus cell1.00infobox
ABCE1Bgeeabdominal wall1.00infobox
ABCE1BgeeGonadal ridge1.00infobox
ABCE1Bgeelacrimal gland1.00infobox
ABCE1Bgeemaxillary prominence1.00infobox
ABCE1Bgeemandibular prominence1.00infobox
ABCE1Bgeedermis1.00infobox
ABCE1Bgeeprimitive streak1.00infobox
ABCE1BioGPSn/a1.00infobox
ABCE1Chr.Chromosome 4 (human)1.00infobox
ABCE1Chr.Chromosome 8 (mouse)1.00infobox
ABCE1DatabasesNCBI: entry; OMA: entry1.00infobox
ABCE1End145,129,524 bp1.00infobox
ABCE1End80,438,369 bp1.00infobox
ABCE1EnsemblENSG000001641631.00infobox
ABCE1Entrez60591.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ABCE1 bring nearby vocabulary together. In this analysis, examples include Member, Cassette and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • ABCE1
    • Member
    • Cassette
    • Gene
    • Inhibitor
    • Translation
    • Atp-binding
    • Eukaryotic
    • Initiation
    • Location
    • Ribonuclease
    • Ribosome
    • Binding
  • abce1
    • Member
    • Cassette
    • Gene
    • Inhibitor
    • Translation
    • Atp-binding
    • Eukaryotic
    • Initiation
    • Location
    • Ribonuclease
    • Ribosome
    • Binding
  • gene
    • Location
    • Chromosome
    • Bp
    • Chr
    • Inhibitor
    • Member
    • Human
    • Band
    • Binding
    • Translation
    • Function
    • Rnase
  • atp-binding cassette (abc) transporters
    • Cassette
    • Member
    • Domains
    • Gene
    • Inhibitor
    • Atp
    • Abc
    • Atp-binding
    • Rnase
    • Abce1
    • Rli
    • Location
  • tumor cell
    • Function
    • Mitochondria
    • Essential
    • Process
    • Translation
    • Protein
    • Initiation
    • Eukaryotic
    • Location
    • Chromosome
    • Export
    • Gene
  • protein
    • Rli
    • Required
    • Translation
    • Well
    • Cell
    • Function
    • Atp
    • Initiation
    • Eukaryotic
    • Export
    • Fe
    • Process
  • eukaryotic translation
    • Subunit
    • Initiation
    • Location
    • Translation
    • Well
    • Binding
    • Chromosome
    • Ribosome
    • Bp
    • Chr
    • Process
    • Cell
  • ribosome biogenesis
    • Ribosome
    • Translation
    • Export
    • Initiation
    • Rli1p
    • Mitochondria
    • Rli
    • Well
    • Eukaryotic
    • Function
    • Location
    • Member

Connections between topic areas Semantic bridges

For ABCE1, one of the stronger structural bridges in this analysis connects ABCE1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ABCE1Overview · splits 12 ⟂ 16
ABCE1Structure · splits 22 ⟂ 6
ABCE1Function · splits 23 ⟂ 5

Map overview Semantic statistics

ABCE1

Nodes28
Edges27
Triples86
Avg. degree1.93
Density0.071429
Components1

Source & methodology

TTTA analyzes the structure around ABCE1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Structure & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ABCE1 · EN edition · Analysis: TopicsToTalkAbout

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