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A-kinase-anchoring protein

The A-kinase anchoring proteins or A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. At least 20 AKAPs have been cloned. There are at least 50 members, often named…

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A-kinase-anchoring protein

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pka akaps regulatory least function proteins bind a-kinase binding subunit locations holoenzyme specific phosphatases anchoring anchor group structurally diverse common

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