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RISC (komplex)

RISC (z angl. RNA-induced silencing complex) je ribonukleoprotein (komplex několika bílkovin a molekuly RNA), který se komplementárně váže na cílovou molekulu mRNA a štěpí ji, případně alespoň blokuje její translaci. Souvisí s jevem zvaným RNA interference. Rozeznává se miRISC, který obsahuje navázanou miRNA, a siRISC, jehož součástí je siRNA. Platí…

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RISC (komplex)

Nodes20
Edges19
Triples0
Avg. degree1.9
Density0.1
Components1

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rna risc mrna ago obsahuje komplex translaci mirna sirna dicer trbp cílovou blokuje mirisc sirisc součástí degradaci proteiny schopná komplexu

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