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Remdesivir

Remdesivir (vývojový kód je GS-5734) je experimentální antivirotikum, které účinkuje jako analog adenosinu. Vyvinula jej americká společnost Gilead Sciences k léčbě infekcí způsobených viry Ebola a Marburg. Ukázalo se však v buňkách být účinné i proti jiným RNA virům včetně koronavirů. Ověřuje se též jeho účinnost proti onemocnění covid-19. V listopadu…

[CS, Czech, Čeština]

Historie & Overview

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Explore the main themes, entities and connections around Remdesivir. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Cesty podání
infuze
ChEMBL ID
CHEMBL4065616
ChemSpider ID
58827832
InChI
InChI=1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35…
Indikace
covid-19 a Ebola
Klasifikace ATC
J05AB16

Topics to explore

A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Historie

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

Remdesivir

Nodes28
Edges27
Triples57
Avg. degree1.93
Density0.071429
Components1

How this topic connects Entity context

Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.

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Remdesivir

Top relations

related to Historie · 19
Remdesivir → Autoři, Dle, Když, Léčba, Mívá, Povolení, Protože, SARS-CoV-2, Společnost Gilead Sciences, Světová, Tomáš Cihlář, Ve, Veklury, Vyskytuje, Vzhledem, Výzkumníci, Washington, WHO, Wu-chanu
related to Česká republika · 13
Remdesivir → Dne, Kralup, Na, Od, Protože, Robert Markovič, Santiago, Státní, SÚKL, Tomáše Cihláře, Vltavou, Věřili, Zda
related to Externí odkazy · 7
Remdesivir → Barbora, Dostupné, Informace, Obrázky, Praha, Státní, Wikimedia CommonsPETEROVÁ
related to Účinnost léku · 4
Remdesivir → Ani, Její, Světová, WHO
Cesty podání · 1
Remdesivir → infuze
ChEMBL ID · 1
Remdesivir → CHEMBL4065616
ChemSpider ID · 1
Remdesivir → 58827832
InChI · 1
Remdesivir → InChI=1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35…
Indikace · 1
Remdesivir → covid-19 a Ebola
Klasifikace ATC · 1
Remdesivir → J05AB16

Important terminology Word statistics

Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.

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Important terminology

2020 proti léku české lék pacientů jeho léčení jako ebola covid-19 who dobu jej společnost světová zdravotnická organizace používání přípravek

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
RemdesivirCesty podáníinfuze1.00infobox
RemdesivirChEMBL IDCHEMBL40656161.00infobox
RemdesivirChemSpider ID588278321.00infobox
RemdesivirInChIInChI=1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35…1.00infobox
RemdesivirIndikacecovid-19 a Ebola1.00infobox
RemdesivirKlasifikace ATCJ05AB161.00infobox
RemdesivirMolární hmotnost602,225 398 71 Da1.00infobox
RemdesivirNázev (INN)remdesivir1.00infobox
RemdesivirNázev podle IUPAC2-ethylbutyl-(2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-kyanoxolan-2-yl]methoxy}(fenoxy)fosforyl]amino}propanoát1.00infobox
RemdesivirPubChem1213040161.00infobox
RemdesivirSMILESNc3ncnn2c3ccc2C(C#N)(C1O)OC(C1O)CO[P](=O)(NC(C)C(=O)OCC(CC)CC)Oc4ccccc41.00infobox
RemdesivirSumární vzorecC₂₇H₃₅N₆O₈P1.00infobox
RemdesivirVedlejší účinkyhepatotoxicita1.00infobox
RemdesivirČíslo CAS1809249-37-31.00infobox

Related concept clusters Concept neighborhoods

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