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Perforin

Perforin je protein produkovaný NK buňkami a cytotoxickými T-lymfocyty. Název „perforin“ je odvozen od jeho fyziologické funkce – perforace cílové membrány. Lidský i myší perforin je kódován genem prf1, tento gen se u obou nachází na chromozomu 10. Strukturně a funkčně je perforin podobný komplementovým složkám C6, C7, C8a, C9, jež tvoří tzv. membránu…

Produkce, Funkce & Overview

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Overview

Produkce

Funkce

Advanced semantic analysis

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Map overview Semantic statistics

Perforin

Nodes32
Edges31
Triples28
Avg. degree1.94
Density0.0625
Components1

How this topic connects Entity context

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Perforin

Top relations

related to Funkce · 11
Perforin → Aktivita, Ca2, Cytotoxická, Druhým, Perforiny, Po, Poté, Pro, Tyto, Velké, Vnitřní
related to Literatura · 11
Perforin → Baran, Dunstone, Immunological Reviews, Immunology Today, Liu, STRUCTURE AND FUNCTION, Trapani, Voskoboinik, Walsh, Whisstock, Young
related to Produkce · 6
Perforin → Golgiho, NK, Sekreční, T-lymfocytem, T-lymfocyty, Uvolňování

Important terminology Word statistics

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Important terminology

perforinu cílové buňky póry nk membrány funkce jsou imunitní aktivita membráně buňkami cytotoxickými t-lymfocyty jeho fyziologické nachází tvoří membránu granzymy

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Perforinrelated to FunkceAktivita0.60section
Perforinrelated to FunkceCa20.60section
Perforinrelated to FunkceCytotoxická0.60section
Perforinrelated to FunkceDruhým0.60section
Perforinrelated to FunkcePo0.60section
Perforinrelated to FunkcePerforiny0.60section
Perforinrelated to FunkcePoté0.60section
Perforinrelated to FunkceVnitřní0.60section
Perforinrelated to FunkcePro0.60section
Perforinrelated to FunkceVelké0.60section
Perforinrelated to FunkceTyto0.60section
Perforinrelated to LiteraturaLiu0.60section

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