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Methotrexát (amethopterin) se využívá v medicíně jako cytostatikum při léčbě nádorů.
Mechanismus účinku & Overview
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jako léčbě datové položky dna revmatoidní cytostatikum nádorů rakovinné buňky amethopterin využívá medicíně mechanismus účinku odkazy reference externí
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Methotrexát | Cesty podání | ústní podání, infuze, nitrosvalová aplikace a Intratekálne podanie | 1.00 | infobox |
| Methotrexát | ChEMBL ID | CHEMBL34259 | 1.00 | infobox |
| Methotrexát | ChemSpider ID | 112728 | 1.00 | infobox |
| Methotrexát | InChI | InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,… | 1.00 | infobox |
| Methotrexát | Indikace | rakovina hlavy a krku, spindle cell sarcoma, rakovina prsu, trophoblastic neoplasm, rakovina jícnu, revmatoidní artritida, juvenilní idiopatická artritida, osteosarkom, mycosis… | 1.00 | infobox |
| Methotrexát | Klasifikace ATC | L04BA01 L04AX03 | 1.00 | infobox |
| Methotrexát | Molární hmotnost | 454,44 g/mol | 1.00 | infobox |
| Methotrexát | Název (INN) | Methotrexát | 1.00 | infobox |
| Methotrexát | Název podle IUPAC | (2S)-2-[(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)amino]pentandiová kyselina | 1.00 | infobox |
| Methotrexát | PubChem | 126941 | 1.00 | infobox |
| Methotrexát | SMILES | CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O | 1.00 | infobox |
| Methotrexát | Sumární vzorec | C20H22N8O5 | 1.00 | infobox |
| Methotrexát | Číslo CAS | 59-05-2 | 1.00 | infobox |
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