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Fysostigmin

Fysostigmin (též známý jako eserin, z „éséré“, západoafrického názvu pro kalabarský bob) je parasympatomimetický alkaloid obsažený v kalabarském bobu, semeni puchýřnatce jedovatého (Physostigma venenosum). Působí jako reverzibilní inhibitor acetylcholinesterázy.

Farmakologie a použití, Overview & Odkazy

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Key facts & relationships

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ChEMBL ID
CHEMBL94
ChemSpider ID
5763
InChI
InChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1
Indikace
glaukom
Klasifikace ATC
S01EB05 V03AB19
Molární hmotnost
275,346 g/mol

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Overview

Farmakologie a použití

Odkazy

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Map overview Semantic statistics

Fysostigmin

Nodes58
Edges57
Triples23
Avg. degree1.97
Density0.034483
Components1

How this topic connects Entity context

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Fysostigmin

Top relations

related to Farmakologie a použití · 7
Fysostigmin → Alzheimerovy, Je, Krus, Nedávno, Nepřímo, Používá, Zřejmě
related to Externí odkazy · 4
Fysostigmin → Obrázky, Ottově, Wikimedia Commons Encyklopedické, Wikizdrojích
ChEMBL ID · 1
Fysostigmin → CHEMBL94
ChemSpider ID · 1
Fysostigmin → 5763
InChI · 1
Fysostigmin → InChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1
Indikace · 1
Fysostigmin → glaukom
Klasifikace ATC · 1
Fysostigmin → S01EB05 V03AB19
Molární hmotnost · 1
Fysostigmin → 275,346 g/mol
Název (INN) · 1
Fysostigmin → Fysostigmin
Název podle IUPAC · 1
Fysostigmin → (3aR,8aS)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl-methylkarbamát

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Important terminology

jako inn předávkování acetylcholinesterázy používá datové položky acetylcholinu parasympatomimetický alkaloid semeni inhibitor syntetizován 1935 léčivo česku léčbě otravě též známý

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FysostigminChEMBL IDCHEMBL941.00infobox
FysostigminChemSpider ID57631.00infobox
FysostigminInChIInChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s11.00infobox
FysostigminIndikaceglaukom1.00infobox
FysostigminKlasifikace ATCS01EB05 V03AB191.00infobox
FysostigminMolární hmotnost275,346 g/mol1.00infobox
FysostigminNázev (INN)Fysostigmin1.00infobox
FysostigminNázev podle IUPAC(3aR,8aS)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl-methylkarbamát1.00infobox
FysostigminPubChem59831.00infobox
FysostigminSMILESCC12CCN(C1N(C3=C2C=C(C=C3)OC(=O)NC)C)C1.00infobox
FysostigminSumární vzorecC15H21N3O21.00infobox
FysostigminČíslo CAS57-47-61.00infobox

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