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EF-ruka (z angl. EF-hand) je proteinový motiv složený ze dvou alfa-helixů („helix-turn-helix“), který váže vápenaté ionty. EF hand byl popsán u kalmodulinu a pojmenován podle toho, že ho tvoří helixy E a F, a že připomíná lidskou ruku v určité poloze – jeho stavbu je možné napodobit pomocí pravé ruky, přičemž palec a ukazovák ukazují ven a zbytek prstů…
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kalmodulinu palec ukazovák helixy zbytek angl proteinový motiv alfa-helixů helix-turn-helix vápenaté proteinkinázy kalpain cytoskeletární alfa-aktinin centrin kalbindin-d28k kalretinin parvalbumin rekoverin
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